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- W3088280721 abstract "Novel Chalcones is considered as an important chemical for the synthesis of various physiological significance and pharmacological utilized molecules. Traditionally, chalcones are prepared by Claisen-Schmidt condensation. The structures of the newly synthesized compounds (3a-3o) were elucidated by IR, 1H-NMR, Mass spectroscopy. All the synthesized compounds (3a-3o) screened for their anti-bacterial activity and anti-inflammatory. Anti bacterial activity of 3b, 3c, 3i and 3o showed more activity and 3d, 3j, 3m and 3n showed less activity when compare with streptomycin. From anti-inflammatory evaluations, dose level of 50mg/kg of test compounds reported significantly higher activity when compared to dose level of 20 mg/kg. Moreover, compound 3d, 3g, 3j and 3o resulted in similar anti-inflammatory activity when compared with Celecoxib." @default.
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- W3088280721 date "2019-01-01" @default.
- W3088280721 modified "2023-09-26" @default.
- W3088280721 title "Microwave-assisted synthesis, anti-bacterial and anti-ammator activity of 3-(Benzo[d]thiazol-2-ylimino)-1-((e)-3-(phenyl) acryloyl) indolin-2-one novel Chalcone derivatives" @default.
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