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• W3088401627 startingPage "193" @default.
• W3088401627 abstract "At present, it is widely recognized that machine perfusion allows for a decreased rate of delayed function of the renal graft and of the risk of liver graft early dysfunction. The aim of the review is to present the actual changes of the donor pool related to prevailing numbers of donors by expanded criteria, to determine the prospects of expanding of the available donor pool based on their selection, as well as development of functional rehabilitation and modification at tissue, cell and molecular levels with the help of perfusion technologies. The article presents the state-of-the art view on the mechanisms of ischemic-reperfusion injury of donor organs, delineates the trends in the maintenance of their viability, and gives the literature data on the role and outlook of perfusion methods in organ transplantation. The authors provide the rationale for a comprehensive systemic approach to the assessment of the functional status of a donor organ with any baseline parameters and discuss a number of theoretical provisions on the implementation of a personalized perfusion approach to ensure the availability of transplantation care." @default.
• W3088401627 created "2020-10-01" @default.
• W3088401627 creator A5001334517 @default.
• W3088401627 creator A5028868133 @default.
• W3088401627 creator A5061994590 @default.
• W3088401627 date "2020-10-05" @default.
• W3088401627 modified "2023-09-25" @default.
• W3088401627 title "Preservation and perfusion rehabilitation of donor organs: achievements of the last decade" @default.
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