FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W308840224> ?p ?o ?g. }

• W308840224 endingPage "1074" @default.
• W308840224 startingPage "1071" @default.
• W308840224 abstract "No AccessJournal of Urology1 May 1986Altered 1-14C Arachidonic Acid Metabolism in Arterial Wall from Patients with Renal Cell Carcinoma Gian Gastone Neri Serneri, Rosanna Abbate, Gian Franco Gensini, Alida Panetta, Gian Carlo Casolo, Alfiero Costantini, Marco Carini, and Cesare Selli Gian Gastone Neri SerneriGian Gastone Neri Serneri More articles by this author , Rosanna AbbateRosanna Abbate More articles by this author , Gian Franco GensiniGian Franco Gensini More articles by this author , Alida PanettaAlida Panetta More articles by this author , Gian Carlo CasoloGian Carlo Casolo More articles by this author , Alfiero CostantiniAlfiero Costantini More articles by this author , Marco CariniMarco Carini More articles by this author , and Cesare SelliCesare Selli More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)45977-5AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail The metabolism of 1-14C arachidonic acid (AA) by arterial wall in patients with renal cell carcinoma and in control patients undergoing nephrectomy was investigated by a high pressure liquid chromatography (HPLC) system. No differences in 1-14C AA uptake and in the total amount of metabolites were found between the two groups, whereas the amounts of cyclooxygenase and lipoxygenase pathway (COP and LOP) metabolites produced by patients with renal cell carcinoma were significantly lower and, respectively, higher than those produced by the control group. The COP/LOP ratio was 7.2±5.5 in the control group in comparison to 1.9±0.5 in renal cell carcinoma patients. The decrease in COP metabolites was due to a markedly reduced synthesis of prostacyclin (PGI2), with no changes in thromboxane B2 (TxB2), prostaglandin F2α (PGF2α) and prostaglandin E2 (PGE2) production. The changes in PGI2 and 12-hydroxy-eicosatetraenoic acid (12-HETE) (metabolite of LOP) vascular production were not related to tumor dimension. The decrease in PGI2 synthesis may represent a factor favoring metastasis and thrombosis in neoplastic patients. © 1986 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 135Issue 5May 1986Page: 1071-1074 Advertisement Copyright & Permissions© 1986 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Gian Gastone Neri Serneri More articles by this author Rosanna Abbate More articles by this author Gian Franco Gensini More articles by this author Alida Panetta More articles by this author Gian Carlo Casolo More articles by this author Alfiero Costantini More articles by this author Marco Carini More articles by this author Cesare Selli More articles by this author Expand All Advertisement PDF DownloadLoading ..." @default.
• W308840224 created "2016-06-24" @default.
• W308840224 creator A5020756755 @default.
• W308840224 creator A5030919371 @default.
• W308840224 creator A5041788136 @default.
• W308840224 creator A5050057021 @default.
• W308840224 creator A5060169707 @default.
• W308840224 creator A5076426908 @default.
• W308840224 creator A5080620058 @default.
• W308840224 creator A5088892512 @default.
• W308840224 date "1986-05-01" @default.
• W308840224 modified "2023-10-14" @default.
• W308840224 title "Altered 1-¹⁴C Arachidonic Acid Metabolism in Arterial Wall from Patients with Renal Cell Carcinoma" @default.
• W308840224 cites W1569167561 @default.
• W308840224 cites W1969464897 @default.
• W308840224 cites W1969559107 @default.
• W308840224 cites W1980030170 @default.
• W308840224 cites W1980581864 @default.
• W308840224 cites W1981581994 @default.
• W308840224 cites W1986268706 @default.
• W308840224 cites W1989591795 @default.
• W308840224 cites W1993401670 @default.
• W308840224 cites W1994624311 @default.
• W308840224 cites W1997746536 @default.
• W308840224 cites W2009225170 @default.
• W308840224 cites W2030087792 @default.
• W308840224 cites W2030500189 @default.
• W308840224 cites W2035660689 @default.
• W308840224 cites W2038042263 @default.
• W308840224 cites W2040353704 @default.
• W308840224 cites W2043655940 @default.
• W308840224 cites W2051338926 @default.
• W308840224 cites W2055682279 @default.
• W308840224 cites W2057995693 @default.
• W308840224 cites W2074425055 @default.
• W308840224 cites W2082547823 @default.
• W308840224 cites W2091034551 @default.
• W308840224 cites W2437161323 @default.
• W308840224 doi "https://doi.org/10.1016/s0022-5347(17)45977-5" @default.
• W308840224 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2937933" @default.
• W308840224 hasPublicationYear "1986" @default.
• W308840224 type Work @default.
• W308840224 sameAs 308840224 @default.
• W308840224 citedByCount "5" @default.
• W308840224 countsByYear W3088402242018 @default.
• W308840224 crossrefType "journal-article" @default.
• W308840224 hasAuthorship W308840224A5020756755 @default.
• W308840224 hasAuthorship W308840224A5030919371 @default.
• W308840224 hasAuthorship W308840224A5041788136 @default.
• W308840224 hasAuthorship W308840224A5050057021 @default.
• W308840224 hasAuthorship W308840224A5060169707 @default.
• W308840224 hasAuthorship W308840224A5076426908 @default.
• W308840224 hasAuthorship W308840224A5080620058 @default.
• W308840224 hasAuthorship W308840224A5088892512 @default.
• W308840224 hasConcept C126322002 @default.
• W308840224 hasConcept C126894567 @default.
• W308840224 hasConcept C134018914 @default.
• W308840224 hasConcept C181199279 @default.
• W308840224 hasConcept C185592680 @default.
• W308840224 hasConcept C2777472916 @default.
• W308840224 hasConcept C2777546739 @default.
• W308840224 hasConcept C2778078955 @default.
• W308840224 hasConcept C55493867 @default.
• W308840224 hasConcept C62231903 @default.
• W308840224 hasConcept C71924100 @default.
• W308840224 hasConceptScore W308840224C126322002 @default.
• W308840224 hasConceptScore W308840224C126894567 @default.
• W308840224 hasConceptScore W308840224C134018914 @default.
• W308840224 hasConceptScore W308840224C181199279 @default.
• W308840224 hasConceptScore W308840224C185592680 @default.
• W308840224 hasConceptScore W308840224C2777472916 @default.
• W308840224 hasConceptScore W308840224C2777546739 @default.
• W308840224 hasConceptScore W308840224C2778078955 @default.
• W308840224 hasConceptScore W308840224C55493867 @default.
• W308840224 hasConceptScore W308840224C62231903 @default.
• W308840224 hasConceptScore W308840224C71924100 @default.
• W308840224 hasIssue "5" @default.
• W308840224 hasLocation W3088402241 @default.
• W308840224 hasLocation W3088402242 @default.
• W308840224 hasOpenAccess W308840224 @default.
• W308840224 hasPrimaryLocation W3088402241 @default.
• W308840224 hasRelatedWork W1966504330 @default.
• W308840224 hasRelatedWork W1979139803 @default.
• W308840224 hasRelatedWork W2009454127 @default.
• W308840224 hasRelatedWork W2030889776 @default.
• W308840224 hasRelatedWork W2032738451 @default.
• W308840224 hasRelatedWork W2037631372 @default.
• W308840224 hasRelatedWork W2040058909 @default.
• W308840224 hasRelatedWork W2041949500 @default.
• W308840224 hasRelatedWork W2132898409 @default.
• W308840224 hasRelatedWork W2748952813 @default.
• W308840224 hasVolume "135" @default.
• W308840224 isParatext "false" @default.
• W308840224 isRetracted "false" @default.
• W308840224 magId "308840224" @default.
• W308840224 workType "article" @default.