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- W3088408738 abstract "Five biologics are approved for the treatment of ulcerative colitis (UC): infliximab, adalimumab, golimumab, vedolizumab, and ustekinumab. These drugs have varying levels of efficacy and are recommended as first-line treatment of moderate to severe UC. There has been only 1 head-to-head trial comparing the efficacy of the biologics, adalimumab and vedolizumab, which has important implications for management. Therapeutic drug monitoring of biologics, especially anti-TNF alpha agents, may improve the long-term efficacy of these agents. The future of treatment may include personalization of medications, based on patient-specific and disease-specific characteristics as well as biomarkers, along with appropriate therapeutic drug monitoring." @default.
- W3088408738 created "2020-10-01" @default.
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- W3088408738 date "2020-12-01" @default.
- W3088408738 modified "2023-10-18" @default.
- W3088408738 title "Biologic Therapy for Ulcerative Colitis" @default.
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- W3088408738 doi "https://doi.org/10.1016/j.gtc.2020.08.002" @default.
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