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- W3088416861 abstract "Introduction: Ophthalmia neonatorum is a severe, sight-threatening condition that occurs in neonates worldwide. Etiological factors include chemical agents, viruses, and bacteria, such as Neisseria gonorrhoeae and Chlamydia trachomatis acquired from infected mothers at birth. Prevalence varies geographically, depending upon socioeconomic conditions, maternal health care, and prophylactic treatments available. Antibiotic resistance, particularly in N. gonorrhoeae, is a major challenge in treating ophthalmia neonatorum. Areas covered: This review explores the epidemiology and diagnosis of ophthalmia neonatorum and analyzes the history and practices of prophylaxis and treatment. In this context, the challenges in treating ophthalmia neonatorum today are discussed and innovations that may overcome these challenges in the future are presented. Advantages and challenges of strategies to prevent ophthalmia neonatorum involving prophylaxis of infants and those using screening and treatment of mothers are explored.Expert commentary: Despite the potential to rapidly cause blindness, there are no universal guidelines for the prevention and treatment of ophthalmia neonatorum. Due to the increasing number of treatment failures, particularly those of extensively drug-resistant N. gonorrhoeae, a pragmatic approach is needed. Enhanced availability of screening and treatment of pregnant mothers, coupled with the development of new antimicrobial ocular prophylaxis and treatments, provide options for a variety of settings." @default.
- W3088416861 created "2020-10-01" @default.
- W3088416861 creator A5050397336 @default.
- W3088416861 creator A5079672920 @default.
- W3088416861 creator A5085107776 @default.
- W3088416861 date "2020-10-15" @default.
- W3088416861 modified "2023-09-30" @default.
- W3088416861 title "Challenges in treating ophthalmia neonatorum" @default.
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