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- W3088513455 abstract "Significance Modification of instinctive behaviors occurs through experience, yet the mechanisms through which this happens have remained largely unknown. Recent studies have shown that potentiation of aggression, an innate behavior, can occur through repeated winning of aggressive encounters. Here, we show that synaptic plasticity at a specific excitatory input to a hypothalamic cell population is correlated with, and required for, the expression of increasingly higher levels of aggressive behavior following aggressive experience. We additionally show that the amplitude and persistence of long-term potentiation at this synapse are influenced by serum testosterone, administration of which can normalize individual differences in the expression of intermale aggression among genetically identical mice." @default.
- W3088513455 created "2020-10-01" @default.
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- W3088513455 date "2020-09-24" @default.
- W3088513455 modified "2023-10-04" @default.
- W3088513455 title "Experience-dependent plasticity in an innate social behavior is mediated by hypothalamic LTP" @default.
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- W3088513455 doi "https://doi.org/10.1073/pnas.2011782117" @default.
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