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- W3088552856 endingPage "2941" @default.
- W3088552856 startingPage "2941" @default.
- W3088552856 abstract "Dietary supplementation based on sea buckthorn and rosehip oils with added chokeberry extract was studied. We added the dietary supplement to the feed mixtures for laboratory animals. The possible toxicological effects and hypocholesterolemic, hepatoprotective activity of the dietary supplement in vivo were studied. After the observation period (6 weeks), no significant changes were found in the mass of organs and blood serum of laboratory animals (p > 0.05). However, there was a decrease in hypercholesterolemic indicators. Regular consumption of sea buckthorn and rosehip oils with added chokeberry extract (dietary supplement “ESB-1”) by laboratory animals inhibited the activity of liver enzymes and increased the antioxidant activity of blood serum (after the subcutaneous injection of sunflower oil/oil solution of carbon tetrachloride) but was not sufficient to bring them to physiological standards. The hypocholesterolemic and antioxidant properties of our dietary supplement already allow us to consider it a component of functional food products or a dietary supplement base. However, the full range of its biologically active properties, including the hepatoprotective function and regulation of metabolic disorders, has not been studied yet, which sets the direction of further research in vivo models and clinical practice to confirm its effectiveness in humans." @default.
- W3088552856 created "2020-10-01" @default.
- W3088552856 creator A5007884636 @default.
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- W3088552856 date "2020-09-25" @default.
- W3088552856 modified "2023-10-07" @default.
- W3088552856 title "Sea Buckthorn and Rosehip Oils with Chokeberry Extract to Prevent Hypercholesterolemia in Mice Caused by a High-Fat Diet In Vivo" @default.
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- W3088552856 doi "https://doi.org/10.3390/nu12102941" @default.
- W3088552856 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7600764" @default.
- W3088552856 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32992796" @default.
- W3088552856 hasPublicationYear "2020" @default.
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