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- W3088573641 abstract "This study aims to investigate alterations of brain connectivity using multivariate electroencephalographic data to provide new insights of the brain connectivity dynamics of dystonia.We recorded electroencephalography (EEG) of patients with right upper limb idiopathic focal dystonia and paired controls during resting state, writing-from-memory, and finger-tapping tasks. We applied power spectrum analyses considering the mu, beta and gamma rhythms of the motor cortex and analyzed brain connectivity networks and microstates (MS).The power spectra results showed that patients had a loss of desynchronization of the beta rhythm during the writing task. We observed differences in the structure of the connective core in beta rhythm, as well as, in the intensity of the patient's hubs observed with basis in path length measures in mu and beta rhythms. Abnormalities were also identified in MS of default mode networks of patients associated with its performances during motor tasks.The EEG connectivity analyses provided interesting insights about the cortical electrophysiological patterns in dystonia, such as loss of event-related desynchronization, changes in the effective connectivity with similar signature to other neurological diseases, indications of alterations in the default-mode-network. Our findings are consistent with previously described connectivity abnormalities in neuroimaging studies confirming that dystonia is a network disorder." @default.
- W3088573641 created "2020-10-01" @default.
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- W3088573641 date "2020-10-29" @default.
- W3088573641 modified "2023-10-09" @default.
- W3088573641 title "Brain connectivity in patients with dystonia during motor tasks" @default.
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- W3088573641 doi "https://doi.org/10.1088/1741-2552/abbbd6" @default.
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