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- W3088796611 abstract "Pemphigoid of the mucous membranes is a chronic autochthonous mucocutaneous bullous disease, in which the production of tissue-bound autoantibodies is directed against 1 or more components of the basement membrane hemidesmosomes. This is a report of case of a 56-year-old male patient, with a symptomatic lesion on gingival mucosa, reddish and scaly. Clinical diagnosis was pemphigoid of the mucous membranes and the lesion was submitted to incisional biopsy. Microscopic examination revealed a fragment of oral mucosa coated with parakeratinized pavement epithelium, exhibiting subepithelial cleft areas. The underlying lamina propria consisted of dense fibrous connective tissue with moderate chronic inflammatory infiltrate. The clinical and histologic characteristics led to the diagnosis of pemphigoid of mucous membranes. The patient was successfully treated with 0.05% clobetasol mouthwash, showing an improvement in the presented clinical picture. The patient’s condition remains stable after 1 year of follow-up. Pemphigoid of the mucous membranes is a chronic autochthonous mucocutaneous bullous disease, in which the production of tissue-bound autoantibodies is directed against 1 or more components of the basement membrane hemidesmosomes. This is a report of case of a 56-year-old male patient, with a symptomatic lesion on gingival mucosa, reddish and scaly. Clinical diagnosis was pemphigoid of the mucous membranes and the lesion was submitted to incisional biopsy. Microscopic examination revealed a fragment of oral mucosa coated with parakeratinized pavement epithelium, exhibiting subepithelial cleft areas. The underlying lamina propria consisted of dense fibrous connective tissue with moderate chronic inflammatory infiltrate. The clinical and histologic characteristics led to the diagnosis of pemphigoid of mucous membranes. The patient was successfully treated with 0.05% clobetasol mouthwash, showing an improvement in the presented clinical picture. The patient’s condition remains stable after 1 year of follow-up." @default.
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- W3088796611 date "2020-09-01" @default.
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- W3088796611 title "PEMPHIGOID OF MUCOUS MEMBRANES REPORT OF A CASE: MANAGEMENT AND FOLLOW-UP EVALUATION" @default.
- W3088796611 doi "https://doi.org/10.1016/j.oooo.2020.04.468" @default.
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