Matches in SemOpenAlex for { <https://semopenalex.org/work/W3088835089> ?p ?o ?g. }
- W3088835089 endingPage "107630" @default.
- W3088835089 startingPage "107630" @default.
- W3088835089 abstract "Amelogenin, a protein critical to enamel formation, is presented as a model for understanding how the structure of biomineralization proteins orchestrate biomineral formation. Amelogenin is the predominant biomineralization protein in the early stages of enamel formation and contributes to the controlled formation of hydroxyapatite (HAP) enamel crystals. The resulting enamel mineral is one of the hardest tissues in the human body and one of the hardest biominerals in nature. Structural studies have been hindered by the lack of techniques to evaluate surface adsorbed proteins and by amelogenin's disposition to self-assemble. Recent advancements in solution and solid state nuclear magnetic resonance (NMR) spectroscopy, atomic force microscopy (AFM), and recombinant isotope labeling strategies are now enabling detailed structural studies. These recent studies, coupled with insights from techniques such as CD and IR spectroscopy and computational methodologies, are contributing to important advancements in our structural understanding of amelogenesis. In this review we focus on recent advances in solution and solid state NMR spectroscopy and in situ AFM that reveal new insights into the secondary, tertiary, and quaternary structure of amelogenin by itself and in contact with HAP. These studies have increased our understanding of the interface between amelogenin and HAP and how amelogenin controls enamel formation." @default.
- W3088835089 created "2020-10-01" @default.
- W3088835089 creator A5033465444 @default.
- W3088835089 creator A5034580690 @default.
- W3088835089 creator A5043081306 @default.
- W3088835089 creator A5056877399 @default.
- W3088835089 creator A5057904055 @default.
- W3088835089 date "2020-12-01" @default.
- W3088835089 modified "2023-10-14" @default.
- W3088835089 title "Controls of nature: Secondary, tertiary, and quaternary structure of the enamel protein amelogenin in solution and on hydroxyapatite" @default.
- W3088835089 cites W131973759 @default.
- W3088835089 cites W1504017858 @default.
- W3088835089 cites W1542723923 @default.
- W3088835089 cites W1550557904 @default.
- W3088835089 cites W1833522613 @default.
- W3088835089 cites W1853019063 @default.
- W3088835089 cites W1868814249 @default.
- W3088835089 cites W1956299500 @default.
- W3088835089 cites W1966521458 @default.
- W3088835089 cites W1966910457 @default.
- W3088835089 cites W1969674072 @default.
- W3088835089 cites W1969794321 @default.
- W3088835089 cites W1974821325 @default.
- W3088835089 cites W1976103991 @default.
- W3088835089 cites W1985877288 @default.
- W3088835089 cites W1990687382 @default.
- W3088835089 cites W1993018794 @default.
- W3088835089 cites W1993236489 @default.
- W3088835089 cites W1995245385 @default.
- W3088835089 cites W1997577800 @default.
- W3088835089 cites W1998351418 @default.
- W3088835089 cites W1998613854 @default.
- W3088835089 cites W2006487061 @default.
- W3088835089 cites W2007016963 @default.
- W3088835089 cites W2007879544 @default.
- W3088835089 cites W2010925591 @default.
- W3088835089 cites W2012640017 @default.
- W3088835089 cites W2013695856 @default.
- W3088835089 cites W2013846682 @default.
- W3088835089 cites W2014756517 @default.
- W3088835089 cites W2015367561 @default.
- W3088835089 cites W2016753466 @default.
- W3088835089 cites W2017192309 @default.
- W3088835089 cites W2017660205 @default.
- W3088835089 cites W2018383388 @default.
- W3088835089 cites W2019511236 @default.
- W3088835089 cites W2019610074 @default.
- W3088835089 cites W2019916074 @default.
- W3088835089 cites W2020120048 @default.
- W3088835089 cites W2020667613 @default.
- W3088835089 cites W2022294251 @default.
- W3088835089 cites W2023354237 @default.
- W3088835089 cites W2023950409 @default.
- W3088835089 cites W2024803155 @default.
- W3088835089 cites W2024903534 @default.
- W3088835089 cites W2025444271 @default.
- W3088835089 cites W2025938842 @default.
- W3088835089 cites W2029487298 @default.
- W3088835089 cites W2030194978 @default.
- W3088835089 cites W2032907555 @default.
- W3088835089 cites W2033029484 @default.
- W3088835089 cites W2035129986 @default.
- W3088835089 cites W2036931844 @default.
- W3088835089 cites W2037152535 @default.
- W3088835089 cites W2039875100 @default.
- W3088835089 cites W2042269368 @default.
- W3088835089 cites W2044279671 @default.
- W3088835089 cites W2044730187 @default.
- W3088835089 cites W2045743883 @default.
- W3088835089 cites W2047311869 @default.
- W3088835089 cites W2048192908 @default.
- W3088835089 cites W2048309531 @default.
- W3088835089 cites W2052701186 @default.
- W3088835089 cites W2053399901 @default.
- W3088835089 cites W2055486718 @default.
- W3088835089 cites W2058638836 @default.
- W3088835089 cites W2059346748 @default.
- W3088835089 cites W2059754495 @default.
- W3088835089 cites W2059974078 @default.
- W3088835089 cites W2060328914 @default.
- W3088835089 cites W2061434026 @default.
- W3088835089 cites W2062081811 @default.
- W3088835089 cites W2062745266 @default.
- W3088835089 cites W2063876533 @default.
- W3088835089 cites W2067620247 @default.
- W3088835089 cites W2069602336 @default.
- W3088835089 cites W2072077083 @default.
- W3088835089 cites W2077828231 @default.
- W3088835089 cites W2078155337 @default.
- W3088835089 cites W2079693436 @default.
- W3088835089 cites W2081885771 @default.
- W3088835089 cites W2084140416 @default.
- W3088835089 cites W2084195624 @default.
- W3088835089 cites W2085220536 @default.
- W3088835089 cites W2087026672 @default.
- W3088835089 cites W2087282067 @default.
- W3088835089 cites W2089968360 @default.
- W3088835089 cites W2092655393 @default.