Matches in SemOpenAlex for { <https://semopenalex.org/work/W3089071011> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W3089071011 abstract "Abstract We propose a hybrid sequential prediction model called “Deep Sequence”, integrating radiomics-engineered imaging features, demographic, and visual factors, with a recursive neural network (RNN) model in the same platform to predict the risk of exudation within a future time-frame in non-exudative AMD eyes. The proposed model provides scores associated with risk of exudation in the short term (within 3 months) and long term (within 21 months), handling challenges related to variability of OCT scan characteristics and the size of the training cohort. We used a retrospective clinical trial dataset that includes 671 AMD fellow eyes with 13,954 observations before any signs of exudation for training and validation in a tenfold cross validation setting. Deep Sequence achieved high performance for the prediction of exudation within 3 months (0.96 ± 0.02 AUCROC) and within 21 months (0.97 ± 0.02 AUCROC) on cross-validation. Training the proposed model on this clinical trial dataset and testing it on an external real-world clinical dataset showed high performance for the prediction within 3-months (0.82 AUCROC) but a clear decrease in performance for the prediction within 21-months (0.68 AUCROC). While performance differences at longer time intervals may be derived from dataset differences, we believe that the high performance and generalizability achieved in short-term predictions may have a high clinical impact allowing for optimal patient follow-up, adding the possibility of more frequent, detailed screening and tailored treatments for those patients with imminent risk of exudation." @default.
- W3089071011 created "2020-10-01" @default.
- W3089071011 creator A5001208801 @default.
- W3089071011 creator A5001530899 @default.
- W3089071011 creator A5004965117 @default.
- W3089071011 creator A5024679224 @default.
- W3089071011 creator A5030704924 @default.
- W3089071011 creator A5035477663 @default.
- W3089071011 creator A5055967429 @default.
- W3089071011 creator A5080764284 @default.
- W3089071011 creator A5087700840 @default.
- W3089071011 date "2020-09-22" @default.
- W3089071011 modified "2023-10-16" @default.
- W3089071011 title "Prediction of age-related macular degeneration disease using a sequential deep learning approach on longitudinal SD-OCT imaging biomarkers" @default.
- W3089071011 cites W1987772140 @default.
- W3089071011 cites W2019656272 @default.
- W3089071011 cites W2035310463 @default.
- W3089071011 cites W2064675550 @default.
- W3089071011 cites W2070847516 @default.
- W3089071011 cites W2124950593 @default.
- W3089071011 cites W2147166769 @default.
- W3089071011 cites W2160226180 @default.
- W3089071011 cites W2174661749 @default.
- W3089071011 cites W2313055258 @default.
- W3089071011 cites W2322965718 @default.
- W3089071011 cites W2589074029 @default.
- W3089071011 cites W2593276269 @default.
- W3089071011 cites W2844103009 @default.
- W3089071011 cites W2886281300 @default.
- W3089071011 cites W2886801379 @default.
- W3089071011 cites W2902341581 @default.
- W3089071011 cites W2911964244 @default.
- W3089071011 cites W2942135141 @default.
- W3089071011 cites W2963339552 @default.
- W3089071011 cites W3007126326 @default.
- W3089071011 doi "https://doi.org/10.1038/s41598-020-72359-y" @default.
- W3089071011 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7508843" @default.
- W3089071011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32963300" @default.
- W3089071011 hasPublicationYear "2020" @default.
- W3089071011 type Work @default.
- W3089071011 sameAs 3089071011 @default.
- W3089071011 citedByCount "30" @default.
- W3089071011 countsByYear W30890710112021 @default.
- W3089071011 countsByYear W30890710112022 @default.
- W3089071011 countsByYear W30890710112023 @default.
- W3089071011 crossrefType "journal-article" @default.
- W3089071011 hasAuthorship W3089071011A5001208801 @default.
- W3089071011 hasAuthorship W3089071011A5001530899 @default.
- W3089071011 hasAuthorship W3089071011A5004965117 @default.
- W3089071011 hasAuthorship W3089071011A5024679224 @default.
- W3089071011 hasAuthorship W3089071011A5030704924 @default.
- W3089071011 hasAuthorship W3089071011A5035477663 @default.
- W3089071011 hasAuthorship W3089071011A5055967429 @default.
- W3089071011 hasAuthorship W3089071011A5080764284 @default.
- W3089071011 hasAuthorship W3089071011A5087700840 @default.
- W3089071011 hasBestOaLocation W30890710111 @default.
- W3089071011 hasConcept C105795698 @default.
- W3089071011 hasConcept C108583219 @default.
- W3089071011 hasConcept C119857082 @default.
- W3089071011 hasConcept C154945302 @default.
- W3089071011 hasConcept C27158222 @default.
- W3089071011 hasConcept C33923547 @default.
- W3089071011 hasConcept C41008148 @default.
- W3089071011 hasConcept C50644808 @default.
- W3089071011 hasConcept C58471807 @default.
- W3089071011 hasConcept C71924100 @default.
- W3089071011 hasConceptScore W3089071011C105795698 @default.
- W3089071011 hasConceptScore W3089071011C108583219 @default.
- W3089071011 hasConceptScore W3089071011C119857082 @default.
- W3089071011 hasConceptScore W3089071011C154945302 @default.
- W3089071011 hasConceptScore W3089071011C27158222 @default.
- W3089071011 hasConceptScore W3089071011C33923547 @default.
- W3089071011 hasConceptScore W3089071011C41008148 @default.
- W3089071011 hasConceptScore W3089071011C50644808 @default.
- W3089071011 hasConceptScore W3089071011C58471807 @default.
- W3089071011 hasConceptScore W3089071011C71924100 @default.
- W3089071011 hasFunder F4320306811 @default.
- W3089071011 hasFunder F4320308990 @default.
- W3089071011 hasIssue "1" @default.
- W3089071011 hasLocation W30890710111 @default.
- W3089071011 hasLocation W30890710112 @default.
- W3089071011 hasOpenAccess W3089071011 @default.
- W3089071011 hasPrimaryLocation W30890710111 @default.
- W3089071011 hasRelatedWork W1958015814 @default.
- W3089071011 hasRelatedWork W2008630378 @default.
- W3089071011 hasRelatedWork W2015341305 @default.
- W3089071011 hasRelatedWork W2035068594 @default.
- W3089071011 hasRelatedWork W2059783833 @default.
- W3089071011 hasRelatedWork W2118717649 @default.
- W3089071011 hasRelatedWork W2413243053 @default.
- W3089071011 hasRelatedWork W410723623 @default.
- W3089071011 hasRelatedWork W4225593417 @default.
- W3089071011 hasRelatedWork W4380075502 @default.
- W3089071011 hasVolume "10" @default.
- W3089071011 isParatext "false" @default.
- W3089071011 isRetracted "false" @default.
- W3089071011 magId "3089071011" @default.
- W3089071011 workType "article" @default.