Matches in SemOpenAlex for { <https://semopenalex.org/work/W3089079758> ?p ?o ?g. }
- W3089079758 abstract "Aluminum is present in medicines and food. Its toxicity induces deleterious effects in various living organisms. At the same time, Hordeum vulgare a cereal known as an important nutritional source and also endowed with bioactive molecules. The objective of this study was to evaluate, on the one hand, the modifications induced by aluminum chloride in Wistar rats at the cerebral level and, on the other hand, to test the efficacy of the barley extract, Hordeum vulgare, (HEV) to restore the harmful effects of this studied metal with a concentration of 13 ml HEV/kg/day for a period of 21 days. The extraction of HEV by maceration resulted in an aqueous extract with a yield of 10.70%. Exposure to AlCl3 at a concentration of 100mg/kg, permitted to observe that the concentration of aluminium at the brain level is significantly high (p<0.05) in the intoxicated rats compared to the control rats. On the other hand, the activity of alkaline phosphatase (PAL), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) indicated a decrease in the intoxicated rats. Indeed, the histological study showed very pronounced lesions in the brains of the poisoned rats resulting in necrosis and cellular spongiosis. In addition, the administration of HEV restored the activity of the various antioxidant enzymes with an improvement in brain tissue architecture in intoxicated rats treated with HEV which justifies the therapeutic virtues of H. vulgare in protecting against aluminium chloride-induced neurotoxicity." @default.
- W3089079758 created "2020-10-01" @default.
- W3089079758 creator A5004218334 @default.
- W3089079758 creator A5017447466 @default.
- W3089079758 creator A5039608013 @default.
- W3089079758 creator A5066149221 @default.
- W3089079758 creator A5079027205 @default.
- W3089079758 creator A5080745331 @default.
- W3089079758 creator A5083790723 @default.
- W3089079758 date "2020-09-12" @default.
- W3089079758 modified "2023-09-26" @default.
- W3089079758 title "Beneficial effect of Hordeum vulgare extract against aluminum chloride induced neurotoxicity in Wistar rats" @default.
- W3089079758 cites W1502877998 @default.
- W3089079758 cites W1546464587 @default.
- W3089079758 cites W1560138211 @default.
- W3089079758 cites W1599342152 @default.
- W3089079758 cites W1836501822 @default.
- W3089079758 cites W1965983315 @default.
- W3089079758 cites W1974307456 @default.
- W3089079758 cites W1977549725 @default.
- W3089079758 cites W1980916936 @default.
- W3089079758 cites W1991874404 @default.
- W3089079758 cites W2006626806 @default.
- W3089079758 cites W2006975593 @default.
- W3089079758 cites W2016358209 @default.
- W3089079758 cites W2016937106 @default.
- W3089079758 cites W2018737017 @default.
- W3089079758 cites W2025192037 @default.
- W3089079758 cites W2037612904 @default.
- W3089079758 cites W2042608077 @default.
- W3089079758 cites W2042928273 @default.
- W3089079758 cites W2043687162 @default.
- W3089079758 cites W2045627495 @default.
- W3089079758 cites W2045736856 @default.
- W3089079758 cites W2049042291 @default.
- W3089079758 cites W2054295934 @default.
- W3089079758 cites W2073092594 @default.
- W3089079758 cites W2078901144 @default.
- W3089079758 cites W2080108051 @default.
- W3089079758 cites W2090387148 @default.
- W3089079758 cites W2096795975 @default.
- W3089079758 cites W2101612148 @default.
- W3089079758 cites W2102394450 @default.
- W3089079758 cites W2104348158 @default.
- W3089079758 cites W2105759347 @default.
- W3089079758 cites W2114383074 @default.
- W3089079758 cites W2133506204 @default.
- W3089079758 cites W2149849166 @default.
- W3089079758 cites W2152067700 @default.
- W3089079758 cites W2169683144 @default.
- W3089079758 cites W2188878280 @default.
- W3089079758 cites W2195785268 @default.
- W3089079758 cites W2321605346 @default.
- W3089079758 cites W2399083761 @default.
- W3089079758 cites W2762961422 @default.
- W3089079758 cites W2770281352 @default.
- W3089079758 cites W2770913560 @default.
- W3089079758 cites W2803345816 @default.
- W3089079758 cites W2889914457 @default.
- W3089079758 cites W2902513420 @default.
- W3089079758 cites W2928901284 @default.
- W3089079758 cites W2955116249 @default.
- W3089079758 cites W3150039193 @default.
- W3089079758 cites W40698810 @default.
- W3089079758 cites W2087951620 @default.
- W3089079758 cites W2186696565 @default.
- W3089079758 cites W2188780607 @default.
- W3089079758 doi "https://doi.org/10.31018/jans.v12i3.2344" @default.
- W3089079758 hasPublicationYear "2020" @default.
- W3089079758 type Work @default.
- W3089079758 sameAs 3089079758 @default.
- W3089079758 citedByCount "0" @default.
- W3089079758 crossrefType "journal-article" @default.
- W3089079758 hasAuthorship W3089079758A5004218334 @default.
- W3089079758 hasAuthorship W3089079758A5017447466 @default.
- W3089079758 hasAuthorship W3089079758A5039608013 @default.
- W3089079758 hasAuthorship W3089079758A5066149221 @default.
- W3089079758 hasAuthorship W3089079758A5079027205 @default.
- W3089079758 hasAuthorship W3089079758A5080745331 @default.
- W3089079758 hasAuthorship W3089079758A5083790723 @default.
- W3089079758 hasBestOaLocation W30890797581 @default.
- W3089079758 hasConcept C178790620 @default.
- W3089079758 hasConcept C185592680 @default.
- W3089079758 hasConcept C2775838275 @default.
- W3089079758 hasConcept C2778004101 @default.
- W3089079758 hasConcept C2778760513 @default.
- W3089079758 hasConcept C2778979269 @default.
- W3089079758 hasConcept C2779491297 @default.
- W3089079758 hasConcept C29730261 @default.
- W3089079758 hasConcept C2993665447 @default.
- W3089079758 hasConcept C31903555 @default.
- W3089079758 hasConcept C46757340 @default.
- W3089079758 hasConcept C55493867 @default.
- W3089079758 hasConcept C59822182 @default.
- W3089079758 hasConcept C86803240 @default.
- W3089079758 hasConcept C98274493 @default.
- W3089079758 hasConceptScore W3089079758C178790620 @default.
- W3089079758 hasConceptScore W3089079758C185592680 @default.
- W3089079758 hasConceptScore W3089079758C2775838275 @default.
- W3089079758 hasConceptScore W3089079758C2778004101 @default.