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- W3089101645 abstract "Bacterial infections are increasingly being recognized as risk factors for the development of adenocarcinomas. The strong epidemiological evidence linking Helicobacter pylori infection to stomach cancer has paved the way to the demonstration that bacterial infections cause DNA damage in the host cells, initiating transformation. In this regard, the role of bacterial genotoxins has become more relevant. Salmonella enterica serovars Typhi and Paratyphi A have been clinically associated with gallbladder cancer. By harnessing the stem cell potential of cells from healthy human gallbladder explant, we regenerated and propagated the epithelium of this organ in vitro and used these cultures to model S. Paratyphi A infection. This study demonstrates the importance of the typhoid toxin, encoded only by these specific serovars, in causing genomic instability in healthy gallbladder cells, posing intoxicated cells at risk of malignant transformation." @default.
- W3089101645 created "2020-10-01" @default.
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- W3089101645 date "2020-10-27" @default.
- W3089101645 modified "2023-10-14" @default.
- W3089101645 title "Genotoxic Effect of <i>Salmonella</i> Paratyphi A Infection on Human Primary Gallbladder Cells" @default.
- W3089101645 cites W1491652527 @default.
- W3089101645 cites W1499306991 @default.
- W3089101645 cites W1529881100 @default.
- W3089101645 cites W1593126602 @default.
- W3089101645 cites W1665091651 @default.
- W3089101645 cites W1759443141 @default.
- W3089101645 cites W1766640855 @default.
- W3089101645 cites W1908169919 @default.
- W3089101645 cites W1966419853 @default.
- W3089101645 cites W1968174606 @default.
- W3089101645 cites W1972604432 @default.
- W3089101645 cites W1972866964 @default.
- W3089101645 cites W1989162293 @default.
- W3089101645 cites W1994464752 @default.
- W3089101645 cites W1994609873 @default.
- W3089101645 cites W1996955003 @default.
- W3089101645 cites W1997333258 @default.
- W3089101645 cites W1999369806 @default.
- W3089101645 cites W1999881785 @default.
- W3089101645 cites W2002513358 @default.
- W3089101645 cites W2014746236 @default.
- W3089101645 cites W2016708272 @default.
- W3089101645 cites W2019405732 @default.
- W3089101645 cites W2019792105 @default.
- W3089101645 cites W2024058225 @default.
- W3089101645 cites W2024164363 @default.
- W3089101645 cites W2026283215 @default.
- W3089101645 cites W2026897048 @default.
- W3089101645 cites W2030915253 @default.
- W3089101645 cites W2050288475 @default.
- W3089101645 cites W2050707891 @default.
- W3089101645 cites W2054511991 @default.
- W3089101645 cites W2077634201 @default.
- W3089101645 cites W2080157242 @default.
- W3089101645 cites W2084133912 @default.
- W3089101645 cites W2085652695 @default.
- W3089101645 cites W2090861902 @default.
- W3089101645 cites W2091272639 @default.
- W3089101645 cites W2094116748 @default.
- W3089101645 cites W2100967517 @default.
- W3089101645 cites W2101369440 @default.
- W3089101645 cites W2105712639 @default.
- W3089101645 cites W2106079980 @default.
- W3089101645 cites W2107300071 @default.
- W3089101645 cites W2110934111 @default.
- W3089101645 cites W2115220730 @default.
- W3089101645 cites W2116137883 @default.
- W3089101645 cites W2134550810 @default.
- W3089101645 cites W2139175224 @default.
- W3089101645 cites W2140748993 @default.
- W3089101645 cites W2146512944 @default.
- W3089101645 cites W2149266449 @default.
- W3089101645 cites W2149813675 @default.
- W3089101645 cites W2150536023 @default.
- W3089101645 cites W2151917637 @default.
- W3089101645 cites W2152930239 @default.
- W3089101645 cites W2155264803 @default.
- W3089101645 cites W2157010562 @default.
- W3089101645 cites W2162888767 @default.
- W3089101645 cites W2260858654 @default.
- W3089101645 cites W2299725955 @default.
- W3089101645 cites W2318364049 @default.
- W3089101645 cites W2319332114 @default.
- W3089101645 cites W2327892327 @default.
- W3089101645 cites W2341985741 @default.
- W3089101645 cites W2394902142 @default.
- W3089101645 cites W2507916945 @default.
- W3089101645 cites W2508677512 @default.
- W3089101645 cites W2509773862 @default.
- W3089101645 cites W2520461980 @default.
- W3089101645 cites W2557119320 @default.
- W3089101645 cites W2567647827 @default.
- W3089101645 cites W2581326404 @default.
- W3089101645 cites W2597003728 @default.
- W3089101645 cites W2706066070 @default.
- W3089101645 cites W2753150462 @default.
- W3089101645 cites W2788159447 @default.
- W3089101645 cites W3008359597 @default.
- W3089101645 cites W3030039762 @default.
- W3089101645 doi "https://doi.org/10.1128/mbio.01911-20" @default.
- W3089101645 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7512552" @default.
- W3089101645 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32963006" @default.
- W3089101645 hasPublicationYear "2020" @default.
- W3089101645 type Work @default.