FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3089184501> ?p ?o ?g. }

• W3089184501 endingPage "2716" @default.
• W3089184501 startingPage "2705" @default.
• W3089184501 abstract "The aim of this study was to evaluate morphological and immunohistochemical features of tooth extraction sites in rats subjected to different antiresorptive drugs. Wistar rats were allocated into 4 groups according to the treatment: (1) alendronate, (2) raloxifene, (3) strontium ranelate, and (4) control. The animals underwent tooth extraction (60th day of treatment) and afterwards were euthanized (90th day of treatment). Tooth extraction sites were analyzed by means of scanning electron microscopy (SEM), hematoxylin-eosin staining (H&E), and immunohistochemical staining (RANKL and OPG). On H&E analysis, the alendronate group showed greater amounts of non-vital bone, biofilm, inflammatory infiltrate and root fragment, and smaller amount of vital bone. The strontium ranelate group showed great amount of non-vital bone. This group also had lower levels of OPG, while the alendronate group showed lower OPG and RANKL than the other groups. On SEM analysis, the alendronate group showed a considerable number of microcracks on the alveolar bone surface and few Howship lacunae and lack of bone cells as well. The raloxifene, strontium ranelate, and control groups showed a large number of bone cells and Howship lacunae on the bone surface and few microcracks. Alendronate therapy is associated with macro- and microscopic features of medication-related osteonecrosis of the jaw at tooth extraction sites, whereas raloxifene therapy is not, and strontium ranelate therapy is associated with non-vital bone. Osteonecrosis of the jaws is a serious side effect of alendronate therapy, where tooth extraction is a major risk factor. Considering the significant number of patients undergoing antiresorptive therapies worldwide, the present study investigated whether raloxifene and strontium ranelate interfere with bone repair after tooth extraction in a similar way to bisphosphonates." @default.
• W3089184501 created "2020-10-01" @default.
• W3089184501 creator A5029312477 @default.
• W3089184501 creator A5050745603 @default.
• W3089184501 creator A5058037391 @default.
• W3089184501 creator A5082228994 @default.
• W3089184501 date "2020-09-23" @default.
• W3089184501 modified "2023-10-16" @default.
• W3089184501 title "Morphological and immunohistochemical features of tooth extraction sites in rats treated with alendronate, raloxifene, or strontium ranelate" @default.
• W3089184501 cites W105651026 @default.
• W3089184501 cites W1817998544 @default.
• W3089184501 cites W1821758927 @default.
• W3089184501 cites W1932145441 @default.
• W3089184501 cites W1984723240 @default.
• W3089184501 cites W1991982980 @default.
• W3089184501 cites W1995038019 @default.
• W3089184501 cites W1999372546 @default.
• W3089184501 cites W2002978754 @default.
• W3089184501 cites W2004189107 @default.
• W3089184501 cites W2006807516 @default.
• W3089184501 cites W2009682500 @default.
• W3089184501 cites W2014932918 @default.
• W3089184501 cites W2019076654 @default.
• W3089184501 cites W2031675678 @default.
• W3089184501 cites W2058889454 @default.
• W3089184501 cites W2066379390 @default.
• W3089184501 cites W2076804839 @default.
• W3089184501 cites W2078445417 @default.
• W3089184501 cites W2087913054 @default.
• W3089184501 cites W2098193961 @default.
• W3089184501 cites W2116557384 @default.
• W3089184501 cites W2139093121 @default.
• W3089184501 cites W2146050863 @default.
• W3089184501 cites W2150354699 @default.
• W3089184501 cites W2171709369 @default.
• W3089184501 cites W2255461676 @default.
• W3089184501 cites W2293789307 @default.
• W3089184501 cites W2411254214 @default.
• W3089184501 cites W2520532275 @default.
• W3089184501 cites W2567225729 @default.
• W3089184501 cites W2752452500 @default.
• W3089184501 cites W2767402465 @default.
• W3089184501 cites W2775638715 @default.
• W3089184501 cites W2781797089 @default.
• W3089184501 cites W2783618252 @default.
• W3089184501 cites W2791031405 @default.
• W3089184501 cites W2802751184 @default.
• W3089184501 cites W2892203530 @default.
• W3089184501 cites W2910266122 @default.
• W3089184501 cites W2912595340 @default.
• W3089184501 cites W2915076599 @default.
• W3089184501 cites W2965423269 @default.
• W3089184501 cites W2968561366 @default.
• W3089184501 cites W3006754541 @default.
• W3089184501 cites W3016000960 @default.
• W3089184501 cites W3047175119 @default.
• W3089184501 cites W4296816736 @default.
• W3089184501 cites W2736008047 @default.
• W3089184501 doi "https://doi.org/10.1007/s00784-020-03585-x" @default.
• W3089184501 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32968945" @default.
• W3089184501 hasPublicationYear "2020" @default.
• W3089184501 type Work @default.
• W3089184501 sameAs 3089184501 @default.
• W3089184501 citedByCount "5" @default.
• W3089184501 countsByYear W30891845012021 @default.
• W3089184501 countsByYear W30891845012022 @default.
• W3089184501 crossrefType "journal-article" @default.
• W3089184501 hasAuthorship W3089184501A5029312477 @default.
• W3089184501 hasAuthorship W3089184501A5050745603 @default.
• W3089184501 hasAuthorship W3089184501A5058037391 @default.
• W3089184501 hasAuthorship W3089184501A5082228994 @default.
• W3089184501 hasBestOaLocation W30891845012 @default.
• W3089184501 hasConcept C121608353 @default.
• W3089184501 hasConcept C126322002 @default.
• W3089184501 hasConcept C126894567 @default.
• W3089184501 hasConcept C170493617 @default.
• W3089184501 hasConcept C199343813 @default.
• W3089184501 hasConcept C204232928 @default.
• W3089184501 hasConcept C2776541429 @default.
• W3089184501 hasConcept C2776594446 @default.
• W3089184501 hasConcept C2779428903 @default.
• W3089184501 hasConcept C2779889926 @default.
• W3089184501 hasConcept C2780426850 @default.
• W3089184501 hasConcept C530470458 @default.
• W3089184501 hasConcept C71924100 @default.
• W3089184501 hasConcept C84606932 @default.
• W3089184501 hasConcept C88045685 @default.
• W3089184501 hasConceptScore W3089184501C121608353 @default.
• W3089184501 hasConceptScore W3089184501C126322002 @default.
• W3089184501 hasConceptScore W3089184501C126894567 @default.
• W3089184501 hasConceptScore W3089184501C170493617 @default.
• W3089184501 hasConceptScore W3089184501C199343813 @default.
• W3089184501 hasConceptScore W3089184501C204232928 @default.
• W3089184501 hasConceptScore W3089184501C2776541429 @default.
• W3089184501 hasConceptScore W3089184501C2776594446 @default.
• W3089184501 hasConceptScore W3089184501C2779428903 @default.
• W3089184501 hasConceptScore W3089184501C2779889926 @default.
• W3089184501 hasConceptScore W3089184501C2780426850 @default.

• next