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- W308919783 abstract "Purpose: To determine the effects of desmopressin on coagulation and blood loss in patients undergoing elective partial hepatectomy. Methods: A randomized, controlled and double-blind study on 59 patients who received either 0.3 µg·kg –1 of desmopressin or an equal volume of normal saline (control) infused intravenously over 20 min after induction of general anesthesia. Results: There was an increase in plasma levels of factors VIII and von Willebrand after the infusion of study drug in both groups (P < 0.001). The activated partial thromboplastin time was shortened in Group D whereas prothrombin time was prolonged in Group C; (P = 0.02). A large range of intraoperative blood loss (400–7128 mL) was observed, with no significant differences between groups. There were no changes in plasma electrolyte levels or osmolality. Transfusion requirements were similar in both groups." @default.
- W308919783 created "2016-06-24" @default.
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- W308919783 date "2003-01-01" @default.
- W308919783 modified "2023-09-27" @default.
- W308919783 title "Andrew Y.C. Wong MB CHB FHKCA FHKAM,* Michael G. Irwin MB CHB DA FRCA FHKCA FHKAM,* Theresa W.C. Hui MBBS FANZCA FHKCA FHKAM,* Serena K.Y. Fung MBBS FANZCA FHKCA FHKAM,§ S.T. Fan MS MD FRCS FHKCS FHKAM,† Edmond S.K. Ma MBBS MRCP MRCPATH FHKAM‡" @default.
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