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- W3089336248 endingPage "577406" @default.
- W3089336248 startingPage "577406" @default.
- W3089336248 abstract "<h2>Abstract</h2> The brain derived neurotrophic factor (BDNF) is a crucial neuromodulator in pain transmission both in peripheral and central nervous system (CNS). Despite evidence of a pro-nociceptive role of BDNF, recent studies have reported contrasting results, including anti-nociceptive and anti-inflammatory activities. Moreover, BDNF polymorphisms can interfere with BDNF role in pain perception. In Val66Met carriers, the Met allele may have a dual role, with anti-nociceptive actions in normal condition and pro-nociceptive effects during chronic pain. In order to elucidate the main effects of BDNF in nociception, we reviewed the main characteristics of this neurotrophin, focusing on its involvement in pain." @default.
- W3089336248 created "2020-10-01" @default.
- W3089336248 creator A5038003942 @default.
- W3089336248 creator A5038942440 @default.
- W3089336248 creator A5043832099 @default.
- W3089336248 creator A5050835352 @default.
- W3089336248 date "2020-12-01" @default.
- W3089336248 modified "2023-10-18" @default.
- W3089336248 title "The emerging role of the BDNF-TrkB signaling pathway in the modulation of pain perception" @default.
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