FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3089410129> ?p ?o ?g. }

• W3089410129 endingPage "1777" @default.
• W3089410129 startingPage "1762" @default.
• W3089410129 abstract "Higher cognitive functions in autism spectrum disorder (ASD) are characterized by impairments in executive functions (EF). While some research attributes this to an overreliance of the prefrontal cortex (PFC), others demonstrate poor recruitment of the PFC in individuals with ASD. In order to assess the emerging consensus across neuroimaging studies of EF in ASD, the current study used a coordinate‐based activation likelihood estimation (ALE) analysis of 16 functional magnetic resonance imaging (fMRI) studies, resulting in a meta‐analysis of data from 739 participants (356 ASD, 383 typically developing [TD] individuals) ranging from 7 to 52 years of age. Within‐group analysis of EF tasks revealed that both TD and ASD participants had significant activity in PFC regions. Analysis of group differences indicated greater activation in ASD, relative to TD participants, in the right middle frontal gyrus and the anterior cingulate cortex, and lesser activation in the bilateral middle frontal, left inferior frontal gyrus, right inferior parietal lobule, and precuneus. Although both ASD and TD participants showed similar PFC activation, there was differential recruitment of wider network of EF regions such as the IPL in ASD participants. The under‐recruitment of parietal regions may be due to poor connectivity of the frontoparietal networks with other regions during EF tasks or a restricted executive network in ASD participants which is limited primarily to the PFC. These results support the executive dysfunction hypothesis of ASD and suggests that poor frontoparietal recruitment may underlie some of the EF difficulties individuals with ASD experience. Lay Summary This study reports a meta‐analysis of 16 brain imaging studies of executive functions (EF) in individuals with autism spectrum disorder (ASD). While parts of the brain's EF network is activated in both ASD and control participants, the ASD group does not activate a wider network of EF regions such as the parietal cortex. This may be due to poor EF network connectivity, or a constrained EF network in ASD participants. These results may underlie some of the EF difficulties individuals with ASD experience. Autism Res 2020, 13: 1762–1777. © 2020 International Society for Autism Research and Wiley Periodicals LLC" @default.
• W3089410129 created "2020-10-08" @default.
• W3089410129 creator A5017834687 @default.
• W3089410129 creator A5084354902 @default.
• W3089410129 date "2020-10-01" @default.
• W3089410129 modified "2023-10-17" @default.
• W3089410129 title "Frontoparietal Network in Executive Functioning in Autism Spectrum Disorder" @default.
• W3089410129 cites W1515602587 @default.
• W3089410129 cites W1518078773 @default.
• W3089410129 cites W1899215478 @default.
• W3089410129 cites W19462567 @default.
• W3089410129 cites W1970695058 @default.
• W3089410129 cites W1976980285 @default.
• W3089410129 cites W1978855114 @default.
• W3089410129 cites W1980432894 @default.
• W3089410129 cites W1987521153 @default.
• W3089410129 cites W1991942804 @default.
• W3089410129 cites W1994335035 @default.
• W3089410129 cites W1996833675 @default.
• W3089410129 cites W2013683637 @default.
• W3089410129 cites W2018858577 @default.
• W3089410129 cites W2019370496 @default.
• W3089410129 cites W2030458571 @default.
• W3089410129 cites W2031322248 @default.
• W3089410129 cites W2033261051 @default.
• W3089410129 cites W2034362253 @default.
• W3089410129 cites W2036208196 @default.
• W3089410129 cites W2036937027 @default.
• W3089410129 cites W2039845328 @default.
• W3089410129 cites W2044473875 @default.
• W3089410129 cites W2045042192 @default.
• W3089410129 cites W2049126844 @default.
• W3089410129 cites W2054054507 @default.
• W3089410129 cites W2057160292 @default.
• W3089410129 cites W2058923243 @default.
• W3089410129 cites W2060259639 @default.
• W3089410129 cites W2068483718 @default.
• W3089410129 cites W2070107423 @default.
• W3089410129 cites W2070562635 @default.
• W3089410129 cites W2081425755 @default.
• W3089410129 cites W2083504120 @default.
• W3089410129 cites W2086098896 @default.
• W3089410129 cites W2086847281 @default.
• W3089410129 cites W2092018014 @default.
• W3089410129 cites W2092948036 @default.
• W3089410129 cites W2097598293 @default.
• W3089410129 cites W2097723363 @default.
• W3089410129 cites W2097801517 @default.
• W3089410129 cites W2098833848 @default.
• W3089410129 cites W2101777433 @default.
• W3089410129 cites W2104858485 @default.
• W3089410129 cites W2105280926 @default.
• W3089410129 cites W2105414250 @default.
• W3089410129 cites W2109231109 @default.
• W3089410129 cites W2114022439 @default.
• W3089410129 cites W2115529264 @default.
• W3089410129 cites W2115610096 @default.
• W3089410129 cites W2116732029 @default.
• W3089410129 cites W2118483696 @default.
• W3089410129 cites W2120731293 @default.
• W3089410129 cites W2124249156 @default.
• W3089410129 cites W2126527128 @default.
• W3089410129 cites W2126543712 @default.
• W3089410129 cites W2128238087 @default.
• W3089410129 cites W2128359078 @default.
• W3089410129 cites W2128815365 @default.
• W3089410129 cites W2131387387 @default.
• W3089410129 cites W2131495391 @default.
• W3089410129 cites W2132069231 @default.
• W3089410129 cites W2139119363 @default.
• W3089410129 cites W2141268338 @default.
• W3089410129 cites W2141805926 @default.
• W3089410129 cites W2143909130 @default.
• W3089410129 cites W2144542843 @default.
• W3089410129 cites W2145683440 @default.
• W3089410129 cites W2145729305 @default.
• W3089410129 cites W2147652511 @default.
• W3089410129 cites W2148727977 @default.
• W3089410129 cites W2156102858 @default.
• W3089410129 cites W2158668308 @default.
• W3089410129 cites W2160066016 @default.
• W3089410129 cites W2160388240 @default.
• W3089410129 cites W2163367670 @default.
• W3089410129 cites W2167101525 @default.
• W3089410129 cites W2168286905 @default.
• W3089410129 cites W2169285522 @default.
• W3089410129 cites W2172212100 @default.
• W3089410129 cites W2346291029 @default.
• W3089410129 cites W2550357178 @default.
• W3089410129 cites W2595024471 @default.
• W3089410129 cites W2600700689 @default.
• W3089410129 cites W2609210742 @default.
• W3089410129 cites W2759793327 @default.
• W3089410129 cites W2768745187 @default.
• W3089410129 cites W2807135032 @default.
• W3089410129 cites W2894852863 @default.
• W3089410129 cites W2901615416 @default.
• W3089410129 cites W2933510942 @default.

• next