FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3089558654> ?p ?o ?g. }

• W3089558654 endingPage "302" @default.
• W3089558654 startingPage "288" @default.
• W3089558654 abstract "Abstract Background Major milestones of head and neck carcinogenesis have been associated with various genetic abnormalities; however, a clear picture of the molecular networks deregulated during the carcinogenesis of head and neck squamous cell carcinoma (HNSC) has not yet completely revealed. Methods In this study, we used in silico tools and online data sets to evaluate the underlying reasons for the expressional changes of genes residing within the chromosome 3q and to help understanding their contributions to HNSC carcinogenesis. Results We found that 13 of 20 most upregulated genes in HNSC are localized to 3q. Further analysis revealed a gene signature consisting of DHX36 , OPA1 , and SENP2 , which showed significant correlation in HNSC samples and potentially be deregulated through similar mechanisms including DNA amplification, transcriptional, and posttranscriptional regulation. Conclusions Considering our findings, we suggest DHX36 , OPA1 , and SENP2 genes as overexpressed in HNSC tumors and that might be concurrently involved in HNSC carcinogenesis, tumor progression, and induction of angiogenic pathways." @default.
• W3089558654 created "2020-10-08" @default.
• W3089558654 creator A5055757471 @default.
• W3089558654 creator A5056039703 @default.
• W3089558654 creator A5081976508 @default.
• W3089558654 creator A5086954044 @default.
• W3089558654 date "2020-10-01" @default.
• W3089558654 modified "2023-09-27" @default.
• W3089558654 title "Comprehensive in silico analysis for identification of novel candidate target genes, including <scp>DHX36</scp> , <scp>OPA1</scp> , and <scp>SENP2</scp> , located on chromosome <scp>3q</scp> in head and neck cancers" @default.
• W3089558654 cites W1547593187 @default.
• W3089558654 cites W1651211333 @default.
• W3089558654 cites W1966812518 @default.
• W3089558654 cites W1978678767 @default.
• W3089558654 cites W1985213868 @default.
• W3089558654 cites W2034532011 @default.
• W3089558654 cites W2040191060 @default.
• W3089558654 cites W2055975111 @default.
• W3089558654 cites W2085934079 @default.
• W3089558654 cites W2092910338 @default.
• W3089558654 cites W2096136039 @default.
• W3089558654 cites W2096719769 @default.
• W3089558654 cites W2101117089 @default.
• W3089558654 cites W2107257651 @default.
• W3089558654 cites W2109134155 @default.
• W3089558654 cites W2120521980 @default.
• W3089558654 cites W2130758099 @default.
• W3089558654 cites W2131078746 @default.
• W3089558654 cites W2134719071 @default.
• W3089558654 cites W2139786434 @default.
• W3089558654 cites W2145685078 @default.
• W3089558654 cites W2149441684 @default.
• W3089558654 cites W2150848049 @default.
• W3089558654 cites W2151157780 @default.
• W3089558654 cites W2154606893 @default.
• W3089558654 cites W2156856489 @default.
• W3089558654 cites W2159793493 @default.
• W3089558654 cites W2161053574 @default.
• W3089558654 cites W2162674813 @default.
• W3089558654 cites W2168986424 @default.
• W3089558654 cites W2172079097 @default.
• W3089558654 cites W2215298194 @default.
• W3089558654 cites W2345356016 @default.
• W3089558654 cites W2405344993 @default.
• W3089558654 cites W2474747771 @default.
• W3089558654 cites W2558715006 @default.
• W3089558654 cites W2594214971 @default.
• W3089558654 cites W2607129810 @default.
• W3089558654 cites W2744219985 @default.
• W3089558654 cites W2749613778 @default.
• W3089558654 cites W2751472497 @default.
• W3089558654 cites W2772152366 @default.
• W3089558654 cites W2775993885 @default.
• W3089558654 cites W2782190825 @default.
• W3089558654 cites W2791336431 @default.
• W3089558654 cites W2808136147 @default.
• W3089558654 cites W2808719234 @default.
• W3089558654 cites W2808860884 @default.
• W3089558654 cites W2809487874 @default.
• W3089558654 cites W2885022472 @default.
• W3089558654 cites W2903124842 @default.
• W3089558654 cites W2911410533 @default.
• W3089558654 cites W2912476769 @default.
• W3089558654 cites W2915964837 @default.
• W3089558654 cites W2927137912 @default.
• W3089558654 cites W2946173685 @default.
• W3089558654 cites W2946657092 @default.
• W3089558654 cites W2947151363 @default.
• W3089558654 cites W2947302463 @default.
• W3089558654 cites W2950392781 @default.
• W3089558654 cites W2951833813 @default.
• W3089558654 cites W2953041081 @default.
• W3089558654 cites W2965466411 @default.
• W3089558654 cites W2966871658 @default.
• W3089558654 cites W2967234314 @default.
• W3089558654 cites W2998134588 @default.
• W3089558654 cites W3003273054 @default.
• W3089558654 cites W3005375588 @default.
• W3089558654 cites W3008224982 @default.
• W3089558654 cites W3017034314 @default.
• W3089558654 cites W2152501153 @default.
• W3089558654 doi "https://doi.org/10.1002/hed.26493" @default.
• W3089558654 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33006201" @default.
• W3089558654 hasPublicationYear "2020" @default.
• W3089558654 type Work @default.
• W3089558654 sameAs 3089558654 @default.
• W3089558654 citedByCount "2" @default.
• W3089558654 countsByYear W30895586542022 @default.
• W3089558654 crossrefType "journal-article" @default.
• W3089558654 hasAuthorship W3089558654A5055757471 @default.
• W3089558654 hasAuthorship W3089558654A5056039703 @default.
• W3089558654 hasAuthorship W3089558654A5081976508 @default.
• W3089558654 hasAuthorship W3089558654A5086954044 @default.
• W3089558654 hasConcept C104317684 @default.
• W3089558654 hasConcept C121608353 @default.
• W3089558654 hasConcept C153911025 @default.
• W3089558654 hasConcept C2775905019 @default.
• W3089558654 hasConcept C2776530083 @default.
• W3089558654 hasConcept C2776833033 @default.

• next