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- W3089596597 abstract "Ammonia is toxic to most fish, and its negative effects can be eliminated by nutritional manipulation. In this study, triplicate groups of yellow catfish (0.58 ± 0.03 g) were fed diets supplemented with 0, 0.30 and 0.60 mg selenium (Se) kg−1 diet for 56 days under three ammonia contents (0.00, 5.70 and 11.40 mg L−1 total ammonia nitrogen). The results showed that ammonia toxicity could affects growth (weight gain, feed efficiency ratio, Se contents in muscle and whole body declined) and survival, leads to oxidative stress (total antioxidant capacity, superoxide dismutase, catalase and glutathione peroxidase activities declined and malondialdehyde accumulation), immunosuppression (lysozyme activity, 50% hemolytic complement, immunoglobulin M, respiratory burst and phagocytic index declined) and cytokines release (TNF, IL 1 and IL 8 elevated), induces up-regulation of antioxidant enzymes (Cu/Zn-SOD, Mn-SOD, CAT and GPx), cytokines (TNFα, IL 1 and IL 8) and pro-apoptotic genes (p53, Bax, Cytochrome c, Caspase 3 and Caspase 9) transcription, and down-regulation of anti-apoptotic gene Bcl2 transcription. The dietary Se supplementation could mitigate the adverse effect of ammonia poisoning on fish growth, oxidative damage, immunosuppression and apoptotic." @default.
- W3089596597 created "2020-10-08" @default.
- W3089596597 creator A5019373327 @default.
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- W3089596597 date "2020-12-01" @default.
- W3089596597 modified "2023-10-15" @default.
- W3089596597 title "The protective effects of selenium on chronic ammonia toxicity in yellow catfish (Pelteobagrus fulvidraco)" @default.
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- W3089596597 doi "https://doi.org/10.1016/j.fsi.2020.10.004" @default.
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