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• W3089657191 startingPage "417" @default.
• W3089657191 abstract "Neuromyelitis optica spectrum disorders (NMOSD) are a demyelinating disorder of the central nervous system based on the involvement of the optic nerve and/or spinal cord. The disease is characterized by high recurrence and disability. NMOSD is mainly diagnosed by AQP4-IgG and MOG-IgG. However, there are still some patients with negative or undetermined double-antibody, and AQP4-IgG and MOG-IgG cannot indicate the clinical disease activity. Therefore, it is urgent to explore interesting biomarkers in serum and cerebrospinal fluid to promote early clinical diagnosis and/or as a target for diagnosis and treatment. This article summarized the research progress in serum and cerebrospinal fluid biomarkers of astrocytes, neurons, myelin sheath, and other damage after the onset of NMOSD. Besides the value of microglial activation-related proteins in the diagnosis and treatment of NMOSD was prospected, so as to promote the research progress of NMOSD." @default.
• W3089657191 created "2020-10-08" @default.
• W3089657191 creator A5067985443 @default.
• W3089657191 creator A5079630580 @default.
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• W3089657191 creator A5090462767 @default.
• W3089657191 date "2020-10-06" @default.
• W3089657191 modified "2023-09-25" @default.
• W3089657191 title "Research and progress on biomarkers of neuromyelitis optica spectrum disorders" @default.
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• W3089657191 doi "https://doi.org/10.1080/10799893.2020.1830109" @default.
• W3089657191 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33019871" @default.
• W3089657191 hasPublicationYear "2020" @default.
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