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- W3089701963 abstract "Altered bactericidal activity against Staphylococcus aureus in tuberculous bronchoalveolarlavage fluids. P. Selvaraj, N. Venkataprasad, V.K. Vijayan, P.R. Narayanan. ©ERSJournals Ltd 1994.ABSTRACT: We wished to evaluate the pulmonary defence capacity against commonbacterial infections in patients with pulmonary tuberculosis.Bactericidal activity against Staphylococcus aureus of bronchoalveolar lavage fluids(cell-free supernatants) of patients with active (n=13) and inactive pulmonarytuberculosis (n=8), and normal individuals (n=6), were studied.The 2 and 4 h bactericidal activities were higher than the 0 h activity in lavagefluids of healthy subjects and patients with inactive pulmonary tuberculosis. Activetuberculous lavage fluids were equally competent in their bactericidal activity againstS. aureus at 0 and 2 h, but a reduced S. aureus hilling was seen at 4 h of incubation.Estimation of total phospholipid levels revealed no significant differencebetween the various lavage fluids. This reduced hilling of S. aureus showed a relationshipwith the cellular components (lymphocytes and macrophages) of activetuberculous lavage fluids. A reduced hilling was associated with no lymphocyticalveolitis, and an increased hilling with lymphocytic alveolitis.This study suggests that alveolar lining material of patients with active pulmonarytuberculosis has less bactericidal activity against bacterial infections, such as S.aureus." @default.
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- W3089701963 date "1994-01-01" @default.
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- W3089701963 title "Altered bactericidal activity aginst staphylococcus aureus in tuberculous bronchoalveolr lavage fluids" @default.
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