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- W3089769884 abstract "Discovery proteomics research has made significant progress in the past several years; however, the number of protein biomarkers deployed in clinical practice remains rather limited. There are several scientific and procedural gaps between discovery proteomics research and clinical implementation, which have contributed to poor biomarker validity and few clinical applications. The complexity and low throughput of proteomics approaches have added additional barriers for biomarker assay translation to clinical applications. Recently, targeted proteomics have become a powerful tool to bridge the biomarker discovery to clinical validation. In this perspective, we discuss the challenges and strategies in proteomics research from a clinical perspective, and propose several recommendations for discovery proteomics research to accelerate protein biomarker discovery and translation for future clinical applications." @default.
- W3089769884 created "2020-10-08" @default.
- W3089769884 creator A5007779904 @default.
- W3089769884 creator A5058845265 @default.
- W3089769884 date "2020-10-01" @default.
- W3089769884 modified "2023-10-16" @default.
- W3089769884 title "Accelerating protein biomarker discovery and translation from proteomics research for clinical utility" @default.
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- W3089769884 doi "https://doi.org/10.4155/bio-2020-0198" @default.
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