FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3089895739> ?p ?o ?g. }

• W3089895739 endingPage "7247" @default.
• W3089895739 startingPage "7247" @default.
• W3089895739 abstract "Prostate cancer is one of the major cancers of the genitourinary tract. High-mobility group box 1 (HMGB1) was suggested as a promising therapeutic target for prostate cancer. In this study, we aim to elucidate the associations of HMGB1 single nucleotide polymorphisms (SNPs) with prostate cancer susceptibility and clinicopathological characteristics. The HMGB1 SNPs rs1412125, rs2249825, rs1045411, and rs1360485 in 579 prostate cancer patients and 579 cancer-free controls were analyzed with real-time polymerase chain reactions (real-time PCR). All of the data were evaluated with SAS statistical software. Our results showed that the HMGB1 rs1045411 T allele genotype was significantly associated with advanced pathologic T stage (odds ratio (OR) = 1.433, 95% confidence interval (CI) = 1.021–2.012; p = 0.037) and pathologic N1 stage (OR = 2.091, 95% CI = 1.160–3.767; p = 0.012), and the rs1360485 polymorphic CT + TT genotype was associated with pathologic Gleason grade group (4 + 5) (OR = 1.583, 95% CI = 1.017–2.462; p = 0.041), pathologic T stage (3 + 4) (OR = 1.482, 95% CI = 1.061–2.070; p = 0.021), and pathologic N1 stage (OR = 2.131, 95% CI = 1.178–3.852; p = 0.011) compared with their wild-type carriers. In conclusion, our results revealed that the HMGB1 SNPs were associated with the clinical status of prostate cancer. The HMGB1 SNPs may have the potential to predict prostate cancer disease progression." @default.
• W3089895739 created "2020-10-08" @default.
• W3089895739 creator A5000924002 @default.
• W3089895739 creator A5009016674 @default.
• W3089895739 creator A5014260545 @default.
• W3089895739 creator A5016758086 @default.
• W3089895739 creator A5024049949 @default.
• W3089895739 creator A5024399146 @default.
• W3089895739 creator A5032024676 @default.
• W3089895739 creator A5038922678 @default.
• W3089895739 creator A5057717715 @default.
• W3089895739 creator A5082130243 @default.
• W3089895739 date "2020-10-03" @default.
• W3089895739 modified "2023-10-14" @default.
• W3089895739 title "The Impact of HMGB1 Polymorphisms on Prostate Cancer Progression and Clinicopathological Characteristics" @default.
• W3089895739 cites W1590909529 @default.
• W3089895739 cites W1974550451 @default.
• W3089895739 cites W2000635377 @default.
• W3089895739 cites W2006629851 @default.
• W3089895739 cites W2029404355 @default.
• W3089895739 cites W2045280239 @default.
• W3089895739 cites W2047471975 @default.
• W3089895739 cites W2058401000 @default.
• W3089895739 cites W2065245558 @default.
• W3089895739 cites W2075035271 @default.
• W3089895739 cites W2100578343 @default.
• W3089895739 cites W2117792530 @default.
• W3089895739 cites W2117977572 @default.
• W3089895739 cites W2148173743 @default.
• W3089895739 cites W2160351999 @default.
• W3089895739 cites W2190504509 @default.
• W3089895739 cites W2313763380 @default.
• W3089895739 cites W2336527076 @default.
• W3089895739 cites W2340422569 @default.
• W3089895739 cites W2344442021 @default.
• W3089895739 cites W2346685985 @default.
• W3089895739 cites W2415642711 @default.
• W3089895739 cites W2524858783 @default.
• W3089895739 cites W2528649042 @default.
• W3089895739 cites W2588866222 @default.
• W3089895739 cites W2593286591 @default.
• W3089895739 cites W2600500432 @default.
• W3089895739 cites W2605070587 @default.
• W3089895739 cites W2712297419 @default.
• W3089895739 cites W2759649948 @default.
• W3089895739 cites W2777231946 @default.
• W3089895739 cites W2781525129 @default.
• W3089895739 cites W2789238142 @default.
• W3089895739 cites W2790293644 @default.
• W3089895739 cites W2796262101 @default.
• W3089895739 cites W2801085592 @default.
• W3089895739 cites W2804436789 @default.
• W3089895739 cites W2884303591 @default.
• W3089895739 cites W2901539272 @default.
• W3089895739 cites W2902286651 @default.
• W3089895739 cites W2903858402 @default.
• W3089895739 cites W2905035919 @default.
• W3089895739 cites W2918776199 @default.
• W3089895739 cites W2947066908 @default.
• W3089895739 cites W2949999931 @default.
• W3089895739 cites W2950383828 @default.
• W3089895739 cites W2951426187 @default.
• W3089895739 cites W2963389137 @default.
• W3089895739 cites W2975345839 @default.
• W3089895739 cites W2978880194 @default.
• W3089895739 cites W3022457222 @default.
• W3089895739 cites W3022810250 @default.
• W3089895739 doi "https://doi.org/10.3390/ijerph17197247" @default.
• W3089895739 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7579148" @default.
• W3089895739 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33023053" @default.
• W3089895739 hasPublicationYear "2020" @default.
• W3089895739 type Work @default.
• W3089895739 sameAs 3089895739 @default.
• W3089895739 citedByCount "6" @default.
• W3089895739 countsByYear W30898957392021 @default.
• W3089895739 countsByYear W30898957392022 @default.
• W3089895739 countsByYear W30898957392023 @default.
• W3089895739 crossrefType "journal-article" @default.
• W3089895739 hasAuthorship W3089895739A5000924002 @default.
• W3089895739 hasAuthorship W3089895739A5009016674 @default.
• W3089895739 hasAuthorship W3089895739A5014260545 @default.
• W3089895739 hasAuthorship W3089895739A5016758086 @default.
• W3089895739 hasAuthorship W3089895739A5024049949 @default.
• W3089895739 hasAuthorship W3089895739A5024399146 @default.
• W3089895739 hasAuthorship W3089895739A5032024676 @default.
• W3089895739 hasAuthorship W3089895739A5038922678 @default.
• W3089895739 hasAuthorship W3089895739A5057717715 @default.
• W3089895739 hasAuthorship W3089895739A5082130243 @default.
• W3089895739 hasBestOaLocation W30898957391 @default.
• W3089895739 hasConcept C104317684 @default.
• W3089895739 hasConcept C121608353 @default.
• W3089895739 hasConcept C126322002 @default.
• W3089895739 hasConcept C135763542 @default.
• W3089895739 hasConcept C142724271 @default.
• W3089895739 hasConcept C143998085 @default.
• W3089895739 hasConcept C146357865 @default.
• W3089895739 hasConcept C151730666 @default.
• W3089895739 hasConcept C153209595 @default.

• next