Matches in SemOpenAlex for { <https://semopenalex.org/work/W3089958063> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W3089958063 endingPage "294" @default.
- W3089958063 startingPage "287" @default.
- W3089958063 abstract "To evaluate the prognostic performance of the Pediatric Index of Mortality 2 (PIM2), ferritin, lactate, C-reactive protein (CRP), and leukocytes, alone and in combination, in pediatric patients with sepsis admitted to the pediatric intensive care unit (PICU).A retrospective study was conducted in a PICU in Brazil. All patients aged 6 months to 18 years admitted with a diagnosis of sepsis were eligible for inclusion. Those with ferritin and C-reactive protein measured within 48h and lactate and leukocytes within 24h of admission were included in the prognostic performance analysis.Of 350 eligible patients with sepsis, 294 had undergone all measurements required for analysis and were included in the study. PIM2, ferritin, lactate, and CRP had good discriminatory power for mortality, with PIM2 and ferritin being superior to CRP. The cutoff values for PIM2 (> 14%), ferritin (> 135ng/mL), lactate (> 1.7mmol/L), and CRP (> 6.7mg/mL) were associated with mortality. The combination of ferritin, lactate, and CRP had a positive predictive value of 43% for mortality, similar to that of PIM2 alone (38.6%). The combined use of the three biomarkers plus PIM2 increased the positive predictive value to 76% and accuracy to 0.945.PIM2, ferritin, lactate, and CRP alone showed good prognostic performance for mortality in pediatric patients older than 6 months with sepsis. When combined, they were able to predict death in three-fourths of the patients with sepsis. Total leukocyte count was not useful as a prognostic marker." @default.
- W3089958063 created "2020-10-08" @default.
- W3089958063 creator A5003181640 @default.
- W3089958063 creator A5013935970 @default.
- W3089958063 creator A5035531872 @default.
- W3089958063 creator A5044214552 @default.
- W3089958063 creator A5051224693 @default.
- W3089958063 creator A5081524645 @default.
- W3089958063 creator A5086555216 @default.
- W3089958063 date "2021-05-01" @default.
- W3089958063 modified "2023-09-30" @default.
- W3089958063 title "Performance of prognostic markers in pediatric sepsis" @default.
- W3089958063 cites W1538170740 @default.
- W3089958063 cites W1978960863 @default.
- W3089958063 cites W1994614315 @default.
- W3089958063 cites W2005118899 @default.
- W3089958063 cites W2007198607 @default.
- W3089958063 cites W2054493330 @default.
- W3089958063 cites W2075482478 @default.
- W3089958063 cites W2076590961 @default.
- W3089958063 cites W2085128602 @default.
- W3089958063 cites W2152575748 @default.
- W3089958063 cites W2157037004 @default.
- W3089958063 cites W2207034536 @default.
- W3089958063 cites W2280404143 @default.
- W3089958063 cites W2328176404 @default.
- W3089958063 cites W2571534087 @default.
- W3089958063 cites W2615260131 @default.
- W3089958063 cites W2751228114 @default.
- W3089958063 cites W2768080064 @default.
- W3089958063 cites W2768607407 @default.
- W3089958063 cites W2804798247 @default.
- W3089958063 cites W2807854357 @default.
- W3089958063 cites W2926446792 @default.
- W3089958063 doi "https://doi.org/10.1016/j.jped.2020.07.008" @default.
- W3089958063 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32991837" @default.
- W3089958063 hasPublicationYear "2021" @default.
- W3089958063 type Work @default.
- W3089958063 sameAs 3089958063 @default.
- W3089958063 citedByCount "12" @default.
- W3089958063 countsByYear W30899580632021 @default.
- W3089958063 countsByYear W30899580632022 @default.
- W3089958063 countsByYear W30899580632023 @default.
- W3089958063 crossrefType "journal-article" @default.
- W3089958063 hasAuthorship W3089958063A5003181640 @default.
- W3089958063 hasAuthorship W3089958063A5013935970 @default.
- W3089958063 hasAuthorship W3089958063A5035531872 @default.
- W3089958063 hasAuthorship W3089958063A5044214552 @default.
- W3089958063 hasAuthorship W3089958063A5051224693 @default.
- W3089958063 hasAuthorship W3089958063A5081524645 @default.
- W3089958063 hasAuthorship W3089958063A5086555216 @default.
- W3089958063 hasBestOaLocation W30899580633 @default.
- W3089958063 hasConcept C126322002 @default.
- W3089958063 hasConcept C167135981 @default.
- W3089958063 hasConcept C187212893 @default.
- W3089958063 hasConcept C2776914184 @default.
- W3089958063 hasConcept C2778319317 @default.
- W3089958063 hasConcept C2778384902 @default.
- W3089958063 hasConcept C2778939556 @default.
- W3089958063 hasConcept C2781195455 @default.
- W3089958063 hasConcept C71924100 @default.
- W3089958063 hasConcept C90924648 @default.
- W3089958063 hasConceptScore W3089958063C126322002 @default.
- W3089958063 hasConceptScore W3089958063C167135981 @default.
- W3089958063 hasConceptScore W3089958063C187212893 @default.
- W3089958063 hasConceptScore W3089958063C2776914184 @default.
- W3089958063 hasConceptScore W3089958063C2778319317 @default.
- W3089958063 hasConceptScore W3089958063C2778384902 @default.
- W3089958063 hasConceptScore W3089958063C2778939556 @default.
- W3089958063 hasConceptScore W3089958063C2781195455 @default.
- W3089958063 hasConceptScore W3089958063C71924100 @default.
- W3089958063 hasConceptScore W3089958063C90924648 @default.
- W3089958063 hasIssue "3" @default.
- W3089958063 hasLocation W30899580631 @default.
- W3089958063 hasLocation W30899580632 @default.
- W3089958063 hasLocation W30899580633 @default.
- W3089958063 hasLocation W30899580634 @default.
- W3089958063 hasLocation W30899580635 @default.
- W3089958063 hasLocation W30899580636 @default.
- W3089958063 hasOpenAccess W3089958063 @default.
- W3089958063 hasPrimaryLocation W30899580631 @default.
- W3089958063 hasRelatedWork W1963617149 @default.
- W3089958063 hasRelatedWork W1979090307 @default.
- W3089958063 hasRelatedWork W2041692577 @default.
- W3089958063 hasRelatedWork W2075482478 @default.
- W3089958063 hasRelatedWork W2147471764 @default.
- W3089958063 hasRelatedWork W2408010109 @default.
- W3089958063 hasRelatedWork W2805891604 @default.
- W3089958063 hasRelatedWork W3029225166 @default.
- W3089958063 hasRelatedWork W3089958063 @default.
- W3089958063 hasRelatedWork W4285138001 @default.
- W3089958063 hasVolume "97" @default.
- W3089958063 isParatext "false" @default.
- W3089958063 isRetracted "false" @default.
- W3089958063 magId "3089958063" @default.
- W3089958063 workType "article" @default.