FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3090090371> ?p ?o ?g. }

• W3090090371 endingPage "3374" @default.
• W3090090371 startingPage "3365" @default.
• W3090090371 abstract "Background One classic traditional Chinese medicine theory is that the “lung and intestine are exterior‐interiorly related”; however, this has not been confirmed experimentally. The aim of this study was to provide a biological basis for the theory by measuring the tissue distribution of andrographolide. Methods Acute pneumonia was induced in a mouse model by repeated stimulation with lipopolysaccharide. The distribution of andrographolide in mice was observed by positron emission tomography (PET) imaging with [ 18 F]‐labeled andrographolide, and changes in the in vivo distribution before and after modeling were compared. Subsequently, the consistency of pathological changes in lung and intestine was confirmed by observation of pathological sections. Finally, the results were verified by cytokine detection. Results The value of organ uptake, pathological changes and inflammatory factor expression of the lung and intestine were consistent. The concentration of andrographolide in the lung and intestine increased significantly, and was confirmed by pathology and enzyme‐linked immunosorbent assays (ELISA). Conclusions Micro‐positron emission tomography (microPET) can be used to visually observe the distribution of medicinal ingredients in vivo, and [ 18 F]‐andrographolide can be used as a tool to assess the interior‐exterior relationship between the lung and intestine." @default.
• W3090090371 created "2020-10-08" @default.
• W3090090371 creator A5026984704 @default.
• W3090090371 creator A5065019003 @default.
• W3090090371 date "2020-10-05" @default.
• W3090090371 modified "2023-09-25" @default.
• W3090090371 title "Biodistribution of andrographolide to assess the interior‐exterior relationship between the lung and intestine using microPET" @default.
• W3090090371 cites W1972901014 @default.
• W3090090371 cites W1976535109 @default.
• W3090090371 cites W1977289780 @default.
• W3090090371 cites W1978049004 @default.
• W3090090371 cites W1983687844 @default.
• W3090090371 cites W2102345655 @default.
• W3090090371 cites W2109225191 @default.
• W3090090371 cites W2124012405 @default.
• W3090090371 cites W2183374027 @default.
• W3090090371 cites W2315049322 @default.
• W3090090371 cites W2575900117 @default.
• W3090090371 cites W2604666863 @default.
• W3090090371 cites W2888452359 @default.
• W3090090371 cites W2914648476 @default.
• W3090090371 cites W2914710029 @default.
• W3090090371 cites W2934116847 @default.
• W3090090371 cites W2939408745 @default.
• W3090090371 cites W2942708015 @default.
• W3090090371 cites W2943089168 @default.
• W3090090371 cites W2943900957 @default.
• W3090090371 cites W2953285292 @default.
• W3090090371 cites W2968670398 @default.
• W3090090371 cites W2969996498 @default.
• W3090090371 cites W2982942149 @default.
• W3090090371 cites W2983916342 @default.
• W3090090371 cites W2994824962 @default.
• W3090090371 cites W2995467079 @default.
• W3090090371 cites W3000834295 @default.
• W3090090371 cites W3001118548 @default.
• W3090090371 cites W3003705707 @default.
• W3090090371 cites W3003749070 @default.
• W3090090371 cites W3004313038 @default.
• W3090090371 cites W3005119027 @default.
• W3090090371 cites W3005637261 @default.
• W3090090371 cites W3165656738 @default.
• W3090090371 doi "https://doi.org/10.1111/1759-7714.13682" @default.
• W3090090371 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7606023" @default.
• W3090090371 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33017514" @default.
• W3090090371 hasPublicationYear "2020" @default.
• W3090090371 type Work @default.
• W3090090371 sameAs 3090090371 @default.
• W3090090371 citedByCount "1" @default.
• W3090090371 countsByYear W30900903712021 @default.
• W3090090371 crossrefType "journal-article" @default.
• W3090090371 hasAuthorship W3090090371A5026984704 @default.
• W3090090371 hasAuthorship W3090090371A5065019003 @default.
• W3090090371 hasBestOaLocation W30900903711 @default.
• W3090090371 hasConcept C110121322 @default.
• W3090090371 hasConcept C126322002 @default.
• W3090090371 hasConcept C134306372 @default.
• W3090090371 hasConcept C142724271 @default.
• W3090090371 hasConcept C150903083 @default.
• W3090090371 hasConcept C207001950 @default.
• W3090090371 hasConcept C207886595 @default.
• W3090090371 hasConcept C2775842073 @default.
• W3090090371 hasConcept C2776280935 @default.
• W3090090371 hasConcept C2777714996 @default.
• W3090090371 hasConcept C2777807558 @default.
• W3090090371 hasConcept C2777882243 @default.
• W3090090371 hasConcept C2781357234 @default.
• W3090090371 hasConcept C2989005 @default.
• W3090090371 hasConcept C33923547 @default.
• W3090090371 hasConcept C71924100 @default.
• W3090090371 hasConcept C86803240 @default.
• W3090090371 hasConcept C98274493 @default.
• W3090090371 hasConceptScore W3090090371C110121322 @default.
• W3090090371 hasConceptScore W3090090371C126322002 @default.
• W3090090371 hasConceptScore W3090090371C134306372 @default.
• W3090090371 hasConceptScore W3090090371C142724271 @default.
• W3090090371 hasConceptScore W3090090371C150903083 @default.
• W3090090371 hasConceptScore W3090090371C207001950 @default.
• W3090090371 hasConceptScore W3090090371C207886595 @default.
• W3090090371 hasConceptScore W3090090371C2775842073 @default.
• W3090090371 hasConceptScore W3090090371C2776280935 @default.
• W3090090371 hasConceptScore W3090090371C2777714996 @default.
• W3090090371 hasConceptScore W3090090371C2777807558 @default.
• W3090090371 hasConceptScore W3090090371C2777882243 @default.
• W3090090371 hasConceptScore W3090090371C2781357234 @default.
• W3090090371 hasConceptScore W3090090371C2989005 @default.
• W3090090371 hasConceptScore W3090090371C33923547 @default.
• W3090090371 hasConceptScore W3090090371C71924100 @default.
• W3090090371 hasConceptScore W3090090371C86803240 @default.
• W3090090371 hasConceptScore W3090090371C98274493 @default.
• W3090090371 hasFunder F4320321001 @default.
• W3090090371 hasFunder F4320323021 @default.
• W3090090371 hasFunder F4320327018 @default.
• W3090090371 hasIssue "11" @default.
• W3090090371 hasLocation W30900903711 @default.
• W3090090371 hasLocation W30900903712 @default.
• W3090090371 hasLocation W30900903713 @default.
• W3090090371 hasOpenAccess W3090090371 @default.

• next