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• W3090136783 abstract "Two isomeric sets of 4-substituted pyridopyrrolopyrimidine nucleobases were prepared through nucleophilic substitutions or cross-coupling reactions of 4-chloropyridopyrrolopyrimidines. The corresponding 4-amino-pyridopyrrolopyrimidines were glycosylated with 5-O-tritylribose using the modified Mitsunobu protocol. Several examples of the title heterocycles showed blue or green fluorescence. Testing of the pyridopyrrolopyrimidine nucleobases for the cytotoxic effect revealed micromolar activity of 4-benzofuryl derivatives in both series, preferentially in multidrug-resistant cancers." @default.
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• W3090136783 date "2020-10-02" @default.
• W3090136783 modified "2023-10-17" @default.
• W3090136783 title "Pyrido-Fused Deazapurine Bases: Synthesis and Glycosylation of 4-Substituted 9<i>H</i>-Pyrido[2′,3′:4,5]- and Pyrido[4′,3′:4,5]pyrrolo[2,3-<i>d</i>]pyrimidines" @default.
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• W3090136783 doi "https://doi.org/10.1021/acsomega.0c04302" @default.
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