FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3090147688> ?p ?o ?g. }

• W3090147688 endingPage "608" @default.
• W3090147688 startingPage "602" @default.
• W3090147688 abstract "Background and purpose Following the commercial availability of nusinersen, there have been a number of new referrals of adults with spinal muscular atrophy (SMA) not regularly followed in tertiary‐care centers or enrolled in any disease registry. Methods We compared demographics and disease characteristics, including assessment of motor and respiratory function, in regularly followed patients and newcomers subdivided according to the SMA type. Results The cohort included 166 adult patients (mean age: 37.09 years): one type I, 65 type II, 99 type III, and one type IV. Of these 166, there were 67 newcomers. There was no significant difference between newcomers and regularly followed patients in relation to age and disease duration. The Hammersmith Functional Motor Scale Expanded and Revised Upper Limb Module scores were higher in the regularly followed patients compared to newcomers in the whole cohort and in both SMA II and II. A difference was also found on ventilatory status ( p = 0.013) and Cobb’s angle >50° ( p = 0.039) between the two subgroups. No difference was found in scoliosis surgery prevalence ( p > 0.05). Conclusions Our results showed differences between the two subgroups, even if less marked in the type III patients. In the type II patients, there was a higher proportion of newcomers who were in the severe end of the spectrum. Of the newcomers, only approximately a third initiated treatment, as opposed to the 51% in the regularly followed patients. The identification of patients who were not part of the registries will help to redefine the overall prevalence of SMA and the occurrence of different phenotypes." @default.
• W3090147688 created "2020-10-08" @default.
• W3090147688 creator A5005240704 @default.
• W3090147688 creator A5008489634 @default.
• W3090147688 creator A5012052284 @default.
• W3090147688 creator A5017152174 @default.
• W3090147688 creator A5019618895 @default.
• W3090147688 creator A5032100811 @default.
• W3090147688 creator A5036573513 @default.
• W3090147688 creator A5042269980 @default.
• W3090147688 creator A5045556511 @default.
• W3090147688 creator A5051966034 @default.
• W3090147688 creator A5054727366 @default.
• W3090147688 creator A5069223646 @default.
• W3090147688 creator A5071125197 @default.
• W3090147688 creator A5076479409 @default.
• W3090147688 creator A5079090935 @default.
• W3090147688 creator A5079310534 @default.
• W3090147688 creator A5084310045 @default.
• W3090147688 creator A5084933471 @default.
• W3090147688 creator A5091829840 @default.
• W3090147688 date "2020-10-31" @default.
• W3090147688 modified "2023-10-18" @default.
• W3090147688 title "Sometimes they come back: New and old spinal muscular atrophy adults in the era of nusinersen" @default.
• W3090147688 cites W1856503184 @default.
• W3090147688 cites W1980477780 @default.
• W3090147688 cites W1999864280 @default.
• W3090147688 cites W2008628221 @default.
• W3090147688 cites W2089476069 @default.
• W3090147688 cites W2094018070 @default.
• W3090147688 cites W2143197369 @default.
• W3090147688 cites W2145090109 @default.
• W3090147688 cites W2147750068 @default.
• W3090147688 cites W2189006175 @default.
• W3090147688 cites W2528264181 @default.
• W3090147688 cites W2765483614 @default.
• W3090147688 cites W2769295220 @default.
• W3090147688 cites W2770254801 @default.
• W3090147688 cites W2771903066 @default.
• W3090147688 cites W2789114047 @default.
• W3090147688 cites W2811369183 @default.
• W3090147688 cites W2895339160 @default.
• W3090147688 cites W2908335062 @default.
• W3090147688 cites W2913924970 @default.
• W3090147688 cites W2971101293 @default.
• W3090147688 cites W2984347447 @default.
• W3090147688 cites W3011851030 @default.
• W3090147688 cites W3012270175 @default.
• W3090147688 cites W3013371597 @default.
• W3090147688 cites W3015763718 @default.
• W3090147688 doi "https://doi.org/10.1111/ene.14567" @default.
• W3090147688 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33012052" @default.
• W3090147688 hasPublicationYear "2020" @default.
• W3090147688 type Work @default.
• W3090147688 sameAs 3090147688 @default.
• W3090147688 citedByCount "8" @default.
• W3090147688 countsByYear W30901476882021 @default.
• W3090147688 countsByYear W30901476882022 @default.
• W3090147688 countsByYear W30901476882023 @default.
• W3090147688 crossrefType "journal-article" @default.
• W3090147688 hasAuthorship W3090147688A5005240704 @default.
• W3090147688 hasAuthorship W3090147688A5008489634 @default.
• W3090147688 hasAuthorship W3090147688A5012052284 @default.
• W3090147688 hasAuthorship W3090147688A5017152174 @default.
• W3090147688 hasAuthorship W3090147688A5019618895 @default.
• W3090147688 hasAuthorship W3090147688A5032100811 @default.
• W3090147688 hasAuthorship W3090147688A5036573513 @default.
• W3090147688 hasAuthorship W3090147688A5042269980 @default.
• W3090147688 hasAuthorship W3090147688A5045556511 @default.
• W3090147688 hasAuthorship W3090147688A5051966034 @default.
• W3090147688 hasAuthorship W3090147688A5054727366 @default.
• W3090147688 hasAuthorship W3090147688A5069223646 @default.
• W3090147688 hasAuthorship W3090147688A5071125197 @default.
• W3090147688 hasAuthorship W3090147688A5076479409 @default.
• W3090147688 hasAuthorship W3090147688A5079090935 @default.
• W3090147688 hasAuthorship W3090147688A5079310534 @default.
• W3090147688 hasAuthorship W3090147688A5084310045 @default.
• W3090147688 hasAuthorship W3090147688A5084933471 @default.
• W3090147688 hasAuthorship W3090147688A5091829840 @default.
• W3090147688 hasBestOaLocation W30901476882 @default.
• W3090147688 hasConcept C114614502 @default.
• W3090147688 hasConcept C126322002 @default.
• W3090147688 hasConcept C141071460 @default.
• W3090147688 hasConcept C144024400 @default.
• W3090147688 hasConcept C149923435 @default.
• W3090147688 hasConcept C161921814 @default.
• W3090147688 hasConcept C1862650 @default.
• W3090147688 hasConcept C187212893 @default.
• W3090147688 hasConcept C2778558090 @default.
• W3090147688 hasConcept C2778871979 @default.
• W3090147688 hasConcept C2779134260 @default.
• W3090147688 hasConcept C2780084366 @default.
• W3090147688 hasConcept C2780955175 @default.
• W3090147688 hasConcept C33923547 @default.
• W3090147688 hasConcept C71924100 @default.
• W3090147688 hasConcept C72563966 @default.
• W3090147688 hasConceptScore W3090147688C114614502 @default.
• W3090147688 hasConceptScore W3090147688C126322002 @default.

• next