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- W3090194512 abstract "La leishmaniose cutanée est une affection parasitaire endémique au Maroc. L’atteinte muqueuse est exceptionnelle. Nous rapportons un cas de leishmaniose cutanée à Leishmania tropica située sur le vermillon, se prolongeant sur le versant muqueux de la lèvre supérieure.Une patiente de 15 ans consultait pour 2 lésions ulcérocroûteuses évoluant depuis 4 mois, l’une siégeant sur la joue gauche et l’autre sur le vermillon de la lèvre supérieure, se prolongeant sur le versant muqueux. L’examen parasitologique confirmait le diagnostic de leishmaniose par la mise en évidence de très nombreux amastigotes de leishmanies. L’isolement de la souche a permis d’identifier une L. tropica. Le traitement par antimoniate de méglumine (Glucantime®) était inefficace. L’évolution était favorable après traitement par fluconazole.Au Maroc, la leishmaniose cutanée avec atteinte muqueuse est rare et correspond le plus souvent à une extension par contiguïté d’une lésion cutanée.Cutaneous leishmaniasis is endemic in Morocco. Mucosal involvement is rare. We report a case in Morocco of cutaneous leishmaniasis of the vermilion border of the upper lip extending to the oral mucosa due to Leishmania tropica.A 15-year-old girl was seen with 2 ulcerated lesions, present for 4 months, situated on the left cheek and vermilion border and extending to the oral mucosa. The diagnosis of leishmaniasis was confirmed by direct examination revealing high numbers of Leishmania amastigotes. Culture of the offending organism in NNN medium and isoenzymatic characterization resulted in identification of L. tropica. Treatment with meglumine antimoniate (Glucantime) was ineffective. The outcome was good after treatment with fluconazole.In Morocco, cutaneous leishmaniasis with mucosal involvement is rare, and usually develops as a complication of cutaneous leishmaniasis via direct extension." @default.
- W3090194512 created "2020-10-08" @default.
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- W3090194512 date "2020-12-01" @default.
- W3090194512 modified "2023-10-17" @default.
- W3090194512 title "Maladies bulleuses auto-immunes en 2020 : des progrès aux paradoxes" @default.
- W3090194512 doi "https://doi.org/10.1016/j.annder.2020.09.002" @default.
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