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- W3090216488 abstract "This article is a tribute to Eli Sercarz and draws on his proposal of a hierarchical order of T-cell determinants in antigen presentation and T-cell activation. Here I revisit the concept of dominance and crypticity in the context of lymphocyte cooperation in the generation of the adaptive immune response, with emphasis on Th-Th cooperation. The remarks made in this article serve as a basis for a reassessment of the unresponsiveness of self-tumor antigens and how to leverage cryptic T-cell determinants operationally to generate antitumor T-cell immunity." @default.
- W3090216488 created "2020-10-08" @default.
- W3090216488 creator A5062279037 @default.
- W3090216488 date "2020-01-01" @default.
- W3090216488 modified "2023-09-26" @default.
- W3090216488 title "Ubi Maior Minor Cessat" @default.
- W3090216488 doi "https://doi.org/10.1615/critrevimmunol.2020034859" @default.
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- W3090216488 hasPublicationYear "2020" @default.
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