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- W3090337488 abstract "Since the presentation and subsequent publication of the International Study Of Comparative Health Effectiveness With Medical And Invasive Approaches (ISCHEMIA) trial, multiple intense debates erupted in the medical press and on social media on the implications of these findings on clinical practice. 1 Maron D.J. Hochman J.S. Reynolds H.R. et al. Initial invasive or conservative strategy for stable coronary disease. N Engl J Med. 2020; 382: 1395-1407 Crossref PubMed Scopus (513) Google Scholar This landmark randomized clinical trial attempted to investigate whether revascularization in addition to optimal medical therapy could lower events in patients with moderate to severe ischemia on physiologic imaging. To better define the cohort, coronary CT angiography was used to exclude patients with left main stenosis and nonobstructive coronary disease prior to randomization. As it is well known, revascularization did not reduce the study primary endpoint compared to optimal medical therapy." @default.
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- W3090337488 date "2021-03-01" @default.
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- W3090337488 title "Does the ISCHEMIA trial provide the appropriate cohort to compare anatomical and physiologic testing?" @default.
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- W3090337488 doi "https://doi.org/10.1016/j.jcct.2020.09.011" @default.
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