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- W3090767360 endingPage "102032" @default.
- W3090767360 startingPage "102032" @default.
- W3090767360 abstract "Phthalocyanines are second-generation photosensitizers with photophysical and photochemical properties improved, in comparison to the first-generation. Also, these have shown to be phototoxic against several types of microorganisms and tumor cells. However, challenges such as low solubility in the physiological environment make its single administration unfeasible. Therefore, this review discusses a unique combination of phthalocyanine-loaded in drug delivery carriers for photodynamic therapy in different pathologies' treatment, including nanoemulsion, liposomes, and lipid nanoparticles in an attempt to overcome low solubility drawback. Furthermore, the latest advances to elucidating its mechanisms of action are shown. Subsequently, the manuscript was divided into ten different types of phthalocyanines for medical applications, with a description of their definitions and applications, summarizing the latest preclinical results founded in recent literature." @default.
- W3090767360 created "2020-10-08" @default.
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- W3090767360 date "2020-12-01" @default.
- W3090767360 modified "2023-10-03" @default.
- W3090767360 title "Prospective application of phthalocyanines in the photodynamic therapy against microorganisms and tumor cells: A mini-review" @default.
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- W3090767360 doi "https://doi.org/10.1016/j.pdpdt.2020.102032" @default.
- W3090767360 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33017659" @default.
- W3090767360 hasPublicationYear "2020" @default.
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