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- W3090805932 abstract "Compounds of oxygen, nitrogen and sulfur containing heterocycles are recognized as important lead compounds in medicinal chemistry. An efficient and rapid synthesis of novel coumarin-thiazolidine-2,4‑dione derivatives (3a-3j) were synthesized by microwave as well as conventional methods. The newly synthesized compounds were characterized by IR, 1H NMR, 13C NMR and Mass spectral studies. The newly synthesized molecules were screened for their anti-inflammatory activity. In vitro study reveals that, compound (3 g) shows significant strong anti-inflammatory broad spectrum activity. Anti-inflammatory activity of compound (3 g) has shown excellent activity with IC50 value of 46.62 µg/mL." @default.
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- W3090805932 date "2020-12-01" @default.
- W3090805932 modified "2023-09-26" @default.
- W3090805932 title "Anti-inflammatory activity of novel (5Z)-3-(2-(2-oxo-2H-chromen-4-yloxy)ethyl)-5-benzylidenethiazolidine-2,4‑dione derivatives: An approach to microwave synthesis" @default.
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- W3090805932 doi "https://doi.org/10.1016/j.cdc.2020.100555" @default.
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