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- W3090837081 endingPage "4366" @default.
- W3090837081 startingPage "4366" @default.
- W3090837081 abstract "This work describes the wettability and biological performance of Zn- and Cu-containing CaP-based coatings prepared by micro-arc oxidation on pure titanium (Ti) and novel Ti-40Nb alloy. Good hydrophilic properties of all the coatings were demonstrated by the low contact angles with liquids, not exceeding 45°. An increase in the applied voltage led to an increase of the coating roughness and porosity, thereby reducing the contact angles to 6° with water and to 17° with glycerol. The free surface energy of 75 ± 3 mJ/m2 for all the coatings were determined. Polar component was calculated as the main component of surface energy, caused by the presence of strong polar PO43− and OH− bonds. In vitro studies showed that low Cu and Zn amounts (~0.4 at.%) in the coatings promoted high motility of human adipose-derived multipotent mesenchymal stromal cells (hAMMSC) on the implant/cell interface and subsequent cell ability to differentiate into osteoblasts. In vivo study demonstrated 100% ectopic bone formation only on the surface of the CaP coating on Ti. The Zn- and Cu-containing CaP coatings on both substrates and the CaP coating on the Ti-40Nb alloy slightly decreased the incidence of ectopic osteogenesis down to 67%. The MAO coatings showed antibacterial efficacy against Staphylococcus aureus and can be arranged as follows: Zn-CaP/Ti > Cu-CaP/TiNb, Zn-CaP/TiNb > Cu-CaP/Ti." @default.
- W3090837081 created "2020-10-08" @default.
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- W3090837081 date "2020-09-30" @default.
- W3090837081 modified "2023-10-17" @default.
- W3090837081 title "Zn- or Cu-containing CaP-Based Coatings Formed by Micro-Arc Oxidation on Titanium and Ti-40Nb Alloy: Part II—Wettability and Biological Performance" @default.
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- W3090837081 doi "https://doi.org/10.3390/ma13194366" @default.
- W3090837081 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7579516" @default.
- W3090837081 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33008055" @default.
- W3090837081 hasPublicationYear "2020" @default.
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