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• W3091034669 abstract "Abstract We present Mustache , a new method for multi-scale detection of chromatin loops from Hi-C and Micro-C contact maps. Mustache employs scale-space theory, a technical advance in computer vision, to detect blob-shaped objects in contact maps. Mustache is scalable to kilobase-resolution maps and reports loops that are highly consistent between replicates and between Hi-C and Micro-C datasets. Compared to other loop callers, such as HiCCUPS and SIP, Mustache recovers a higher number of published ChIA-PET and HiChIP loops as well as loops linking promoters to regulatory elements. Overall, Mustache enables an efficient and comprehensive analysis of chromatin loops. Available at: https://github.com/ay-lab/mustache ." @default.
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• W3091034669 date "2020-09-30" @default.
• W3091034669 modified "2023-10-18" @default.
• W3091034669 title "Mustache: multi-scale detection of chromatin loops from Hi-C and Micro-C maps using scale-space representation" @default.
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• W3091034669 doi "https://doi.org/10.1186/s13059-020-02167-0" @default.
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