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- W3091150140 abstract "弥漫性大B细胞淋巴瘤(DLBCL)是一组生物学高度异质的肿瘤,基于遗传学特点对其区分亚型有助于临床危险度分层并指导精准治疗。近年来,DLBCL的分子分型已由原来单纯基于基因表达水平的起源细胞(COO)分型逐渐过渡到COO分型与侧重于驱动性遗传学异常(包括基因突变、易位及拷贝数改变等)检测的基因分型相结合的阶段。二者结合的分型方法,或许能更好地解释肿瘤的生物学异质性与治疗反应差别。上述分型理论,可能还有待更多的实践加以验证和补充。." @default.
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- W3091150140 date "2020-10-08" @default.
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- W3091150140 title "[Molecular subtyping of diffuse large B-cell lymphoma]." @default.
- W3091150140 doi "https://doi.org/10.3760/cma.j.cn112151-20200803-00617" @default.
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