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- W3091592106 abstract "In response to hypoxia under submergence, plants switch from aerobic respiration to anaerobic fermentation, which leads to the accumulation of the end product, ethanol. We previously reported that Arabidopsis thaliana autophagy-deficient mutants show increased sensitivity to ethanol treatment, indicating that ethanol is likely involved in regulating the autophagy-mediated hypoxia response. Here, using a transcriptomic analysis, we identified 3909 genes in Arabidopsis seedlings that were differentially expressed in response to ethanol treatment, including 2487 upregulated and 1422 downregulated genes. Ethanol treatment significantly upregulated genes involved in autophagy and the detoxification of reactive oxygen species. Using transgenic lines expressing AUTOPHAGY-RELATED PROTEIN 8e fused to green fluorescent protein (GFP-ATG8e), we confirmed that exogenous ethanol treatment promotes autophagosome formation in vivo. Phenotypic analysis showed that deletions in the alcohol dehydrogenase gene in adh1 mutants result in attenuated submergence tolerance, decreased accumulation of ATG proteins, and diminished submergence-induced autophagosome formation. Compared to the submergence-tolerant Arabidopsis accession Columbia (Col-0), the submergence-intolerant accession Landsberg erecta (Ler) displayed hypersensitivity to ethanol treatment; we linked these phenotypes to differences in the functions of ADH1 and the autophagy machinery between these accessions. Thus, ethanol promotes autophagy-mediated submergence tolerance in Arabidopsis." @default.
- W3091592106 created "2020-10-08" @default.
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- W3091592106 date "2020-10-05" @default.
- W3091592106 modified "2023-10-15" @default.
- W3091592106 title "The Anaerobic Product Ethanol Promotes Autophagy-Dependent Submergence Tolerance in Arabidopsis" @default.
- W3091592106 cites W107697700 @default.
- W3091592106 cites W1849762302 @default.
- W3091592106 cites W1967842506 @default.
- W3091592106 cites W1976015745 @default.
- W3091592106 cites W1982578345 @default.
- W3091592106 cites W1986286409 @default.
- W3091592106 cites W1988799657 @default.
- W3091592106 cites W1989799913 @default.
- W3091592106 cites W1991710875 @default.
- W3091592106 cites W1995966034 @default.
- W3091592106 cites W2002100808 @default.
- W3091592106 cites W2006321864 @default.
- W3091592106 cites W2019867369 @default.
- W3091592106 cites W2032168149 @default.
- W3091592106 cites W2037667855 @default.
- W3091592106 cites W2041499579 @default.
- W3091592106 cites W2043837896 @default.
- W3091592106 cites W2051027814 @default.
- W3091592106 cites W2054613425 @default.
- W3091592106 cites W2064146946 @default.
- W3091592106 cites W2066119887 @default.
- W3091592106 cites W2067985330 @default.
- W3091592106 cites W2068847894 @default.
- W3091592106 cites W2070647407 @default.
- W3091592106 cites W2073449221 @default.
- W3091592106 cites W2075218245 @default.
- W3091592106 cites W2081164010 @default.
- W3091592106 cites W2085300535 @default.
- W3091592106 cites W2087205919 @default.
- W3091592106 cites W2087348016 @default.
- W3091592106 cites W2089945341 @default.
- W3091592106 cites W2092495258 @default.
- W3091592106 cites W2096497715 @default.
- W3091592106 cites W2099670806 @default.
- W3091592106 cites W2100002905 @default.
- W3091592106 cites W2107162418 @default.
- W3091592106 cites W2114007504 @default.
- W3091592106 cites W2118818049 @default.
- W3091592106 cites W2118885188 @default.
- W3091592106 cites W2123713398 @default.
- W3091592106 cites W2125429168 @default.
- W3091592106 cites W2127585131 @default.
- W3091592106 cites W2141801282 @default.
- W3091592106 cites W2148587990 @default.
- W3091592106 cites W2151469356 @default.
- W3091592106 cites W2154290787 @default.
- W3091592106 cites W2158217645 @default.
- W3091592106 cites W2159754281 @default.
- W3091592106 cites W2160357297 @default.
- W3091592106 cites W2160842565 @default.
- W3091592106 cites W2162434705 @default.
- W3091592106 cites W2164252992 @default.
- W3091592106 cites W2164935491 @default.
- W3091592106 cites W2164979364 @default.
- W3091592106 cites W2166398931 @default.
- W3091592106 cites W2169395311 @default.
- W3091592106 cites W2177497984 @default.
- W3091592106 cites W2292737287 @default.
- W3091592106 cites W2369934933 @default.
- W3091592106 cites W2472599917 @default.
- W3091592106 cites W2477550927 @default.
- W3091592106 cites W2533355719 @default.
- W3091592106 cites W2569792034 @default.
- W3091592106 cites W2576991587 @default.
- W3091592106 cites W2592774578 @default.
- W3091592106 cites W2598059826 @default.
- W3091592106 cites W2602712815 @default.
- W3091592106 cites W2611604995 @default.
- W3091592106 cites W2623576839 @default.
- W3091592106 cites W2733102393 @default.
- W3091592106 cites W2733369879 @default.
- W3091592106 cites W2743518148 @default.
- W3091592106 cites W2744920020 @default.
- W3091592106 cites W2778119055 @default.
- W3091592106 cites W2793502838 @default.
- W3091592106 cites W2928665623 @default.
- W3091592106 cites W2979446361 @default.
- W3091592106 cites W2985552365 @default.
- W3091592106 cites W86289222 @default.
- W3091592106 doi "https://doi.org/10.3390/ijms21197361" @default.
- W3091592106 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7583018" @default.
- W3091592106 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33028029" @default.
- W3091592106 hasPublicationYear "2020" @default.
- W3091592106 type Work @default.