Matches in SemOpenAlex for { <https://semopenalex.org/work/W3091750031> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W3091750031 endingPage "280" @default.
- W3091750031 startingPage "276" @default.
- W3091750031 abstract "Dapagliflozin is a sodium-glucose co-transporter-2 (SGLT2) inhibitor that has recently been shown to reduce the incidence of reported episodes of atrial fibrillation (AF)/atrial flutter in the DECLARE-TIMI 58 trial. This raises the question regarding whether SGLT2 inhibitors can reduce the incidence of AF in a high-risk population. We searched for trials comparing SGLT2 inhibitors to placebo in high-risk individuals with or without diabetes (ie, cardiovascular and renal outcome trials) and that reported the incidence of AF as a serious adverse event. The EMPA-REG OUTCOME trial, CANVAS, CANVAS-R, the DECLARE-TIMI 58 trial, CREDENCE, DAPA-HF, VERTIS-CV and DAPA-CKD were included. The incidence of AF, reported as a serious adverse event, was 0.9% in individuals who received an SGLT2 inhibitor compared to 1.1% in those who received placebo. Pooled results showed a significantly lower incidence of AF in individuals with and without diabetes (relative risk 0.79, 95% confidence interval 0.67,0.93). This review suggests that there is a significantly lower risk of incident AF for individuals on SGLT2 inhibitors versus placebo. While there was a statistically significant lower incidence of AF, reported as a serious adverse event, more research is needed to evaluate its clinical significance." @default.
- W3091750031 created "2020-10-08" @default.
- W3091750031 creator A5005950432 @default.
- W3091750031 creator A5027721713 @default.
- W3091750031 creator A5085642258 @default.
- W3091750031 creator A5091612546 @default.
- W3091750031 date "2020-10-19" @default.
- W3091750031 modified "2023-10-06" @default.
- W3091750031 title "Sodium‐glucose co‐transporter‐2 inhibitors and atrial fibrillation in the cardiovascular and renal outcome trials" @default.
- W3091750031 cites W2047572350 @default.
- W3091750031 cites W2072677007 @default.
- W3091750031 cites W2115088504 @default.
- W3091750031 cites W2140568388 @default.
- W3091750031 cites W2146264128 @default.
- W3091750031 cites W2418869077 @default.
- W3091750031 cites W2511209897 @default.
- W3091750031 cites W2589084718 @default.
- W3091750031 cites W2626446274 @default.
- W3091750031 cites W2749591576 @default.
- W3091750031 cites W2756811299 @default.
- W3091750031 cites W2779106648 @default.
- W3091750031 cites W2779223875 @default.
- W3091750031 cites W2781483265 @default.
- W3091750031 cites W2900413769 @default.
- W3091750031 cites W2913672674 @default.
- W3091750031 cites W2939222610 @default.
- W3091750031 cites W2948602156 @default.
- W3091750031 cites W2953049681 @default.
- W3091750031 cites W2965578843 @default.
- W3091750031 cites W2969786006 @default.
- W3091750031 cites W2972107819 @default.
- W3091750031 cites W2974260792 @default.
- W3091750031 cites W2989579906 @default.
- W3091750031 cites W2999986417 @default.
- W3091750031 cites W3004319546 @default.
- W3091750031 cites W3035488153 @default.
- W3091750031 cites W3038036007 @default.
- W3091750031 cites W3047122516 @default.
- W3091750031 cites W3081830235 @default.
- W3091750031 cites W3088173406 @default.
- W3091750031 cites W3089283105 @default.
- W3091750031 doi "https://doi.org/10.1111/dom.14211" @default.
- W3091750031 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33001548" @default.
- W3091750031 hasPublicationYear "2020" @default.
- W3091750031 type Work @default.
- W3091750031 sameAs 3091750031 @default.
- W3091750031 citedByCount "52" @default.
- W3091750031 countsByYear W30917500312021 @default.
- W3091750031 countsByYear W30917500312022 @default.
- W3091750031 countsByYear W30917500312023 @default.
- W3091750031 crossrefType "journal-article" @default.
- W3091750031 hasAuthorship W3091750031A5005950432 @default.
- W3091750031 hasAuthorship W3091750031A5027721713 @default.
- W3091750031 hasAuthorship W3091750031A5085642258 @default.
- W3091750031 hasAuthorship W3091750031A5091612546 @default.
- W3091750031 hasConcept C104317684 @default.
- W3091750031 hasConcept C126322002 @default.
- W3091750031 hasConcept C149011108 @default.
- W3091750031 hasConcept C161573976 @default.
- W3091750031 hasConcept C164705383 @default.
- W3091750031 hasConcept C185592680 @default.
- W3091750031 hasConcept C2779161974 @default.
- W3091750031 hasConcept C2779306644 @default.
- W3091750031 hasConcept C55493867 @default.
- W3091750031 hasConcept C71924100 @default.
- W3091750031 hasConcept C98274493 @default.
- W3091750031 hasConceptScore W3091750031C104317684 @default.
- W3091750031 hasConceptScore W3091750031C126322002 @default.
- W3091750031 hasConceptScore W3091750031C149011108 @default.
- W3091750031 hasConceptScore W3091750031C161573976 @default.
- W3091750031 hasConceptScore W3091750031C164705383 @default.
- W3091750031 hasConceptScore W3091750031C185592680 @default.
- W3091750031 hasConceptScore W3091750031C2779161974 @default.
- W3091750031 hasConceptScore W3091750031C2779306644 @default.
- W3091750031 hasConceptScore W3091750031C55493867 @default.
- W3091750031 hasConceptScore W3091750031C71924100 @default.
- W3091750031 hasConceptScore W3091750031C98274493 @default.
- W3091750031 hasFunder F4320320945 @default.
- W3091750031 hasIssue "1" @default.
- W3091750031 hasLocation W30917500311 @default.
- W3091750031 hasOpenAccess W3091750031 @default.
- W3091750031 hasPrimaryLocation W30917500311 @default.
- W3091750031 hasRelatedWork W1967841144 @default.
- W3091750031 hasRelatedWork W2018480046 @default.
- W3091750031 hasRelatedWork W2312606134 @default.
- W3091750031 hasRelatedWork W2319489406 @default.
- W3091750031 hasRelatedWork W2333279585 @default.
- W3091750031 hasRelatedWork W2603808924 @default.
- W3091750031 hasRelatedWork W2889073610 @default.
- W3091750031 hasRelatedWork W2948755024 @default.
- W3091750031 hasRelatedWork W4241831378 @default.
- W3091750031 hasRelatedWork W4244112197 @default.
- W3091750031 hasVolume "23" @default.
- W3091750031 isParatext "false" @default.
- W3091750031 isRetracted "false" @default.
- W3091750031 magId "3091750031" @default.
- W3091750031 workType "article" @default.