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- W3091780281 abstract "234 Background: There is an urgent need to assess quality of cancer care in Latin America, especially amongst the most prevalent tumors, such as colorectal cancer. The main aim of this study was to assess adherence to previously validated quality indicators (QIs) for colorectal cancer in the context of a public healthcare provider in Uruguay. Methods: Data regarding all colorectal cancers registered between January 1, 2008 and December 31, 2019 at the National Cancer Institute of Montevideo was collected through retrospective analysis of medical records. We used 12 QIs (4 diagnostic, 7 treatment,1 surveillance) validated in previous publications. Each QI was analyzed as a proportion (%) and compared to target values with 95% confidence interval. Results: A total of 808 colorectal cancers were identified; only 10.1% were diagnosed by screening, 87% were diagnosed after reporting symptoms and 29.5% underwent emergency surgery. A complete preoperative colonoscopy was performed in 47% of patients, 64% had a CT-TAP scan and 63% of locally advanced rectal cancers had staging MRI prior to definitive treatment. Surgical resection with tumor free margins was obtained in 97% of cases, and for 68% at least 12 lymph nodes were examined. Neoadjuvant radiotherapy plus chemotherapy as first therapeutic strategy was implemented in 79% of rectal cancers. High risk stage II and III colon cancer received adjuvant chemotherapy within 16 weeks of surgery in 72,9% of cases. Postoperative follow up with CEA was registered in 97% of our series. Most patients ≤ 75 years of age with metastatic unresectable colorectal cancer at diagnosis underwent first-line chemotherapy or bio-chemotherapy. A low level of adherence was identified in micro-satellite and RAS status testing, 16 and 22 patients respectively. Conclusions: This study is a pioneer study in Latin America. The standardization of QI definition to achieve interregional comparative goals remains an unmet need.Our data indicates there is much to improve in early diagnosis, preoperative staging, neoadjuvant therapy and molecular testing. QI indicators in surgery and adjuvant chemotherapy prescription are similar to those reported in international studies." @default.
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- W3091780281 date "2020-10-10" @default.
- W3091780281 modified "2023-09-26" @default.
- W3091780281 title "Quality indicators of colorectal cancer care in a public healthcare institution in Uruguay: Results from a retrospective population-based study." @default.
- W3091780281 doi "https://doi.org/10.1200/jco.2020.38.29_suppl.234" @default.
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