Matches in SemOpenAlex for { <https://semopenalex.org/work/W3091788260> ?p ?o ?g. }
- W3091788260 abstract "Abstract Spliceosomal introns interrupt nuclear genes and are removed from RNA transcripts (“spliced”) by machinery called spliceosomes. While the vast majority of spliceosomal introns are removed by the so-called major spliceosome, diverse eukaryotes also contain a mysterious second form, the minor spliceosome, and associated introns [1–3]. In all characterized species, minor introns are distinguished by several features, including being rare in the genome (∼0.5% of all introns) [4–6], containing extended evolutionary-conserved splicing sites [4,5,7,8], being generally ancient [9,10] and being inefficiently spliced [11–13]. Here, we report a remarkable exception in the slime mold Physarum polycephalum . The P. polycephalum genome contains > 20,000 minor introns—25 times more than any other species—with transformed splicing signals that have co-evolved with the spliceosome due to massive gain of efficiently spliced minor introns. These results reveal an unappreciated dynamism of minor spliceosomal introns and spliceosomal introns in general." @default.
- W3091788260 created "2020-10-15" @default.
- W3091788260 creator A5009940856 @default.
- W3091788260 creator A5045315721 @default.
- W3091788260 creator A5072611345 @default.
- W3091788260 date "2020-10-12" @default.
- W3091788260 modified "2023-09-23" @default.
- W3091788260 title "Expansion and transformation of the minor spliceosomal system in the slime mold Physarum polycephalum" @default.
- W3091788260 cites W1518186650 @default.
- W3091788260 cites W2011657487 @default.
- W3091788260 cites W2020240988 @default.
- W3091788260 cites W2021525576 @default.
- W3091788260 cites W2027265085 @default.
- W3091788260 cites W2035136477 @default.
- W3091788260 cites W2036969473 @default.
- W3091788260 cites W2038473580 @default.
- W3091788260 cites W2050502168 @default.
- W3091788260 cites W2056617805 @default.
- W3091788260 cites W2064594580 @default.
- W3091788260 cites W2066876408 @default.
- W3091788260 cites W2074097219 @default.
- W3091788260 cites W2083010720 @default.
- W3091788260 cites W2083303900 @default.
- W3091788260 cites W2098937968 @default.
- W3091788260 cites W2101631559 @default.
- W3091788260 cites W2110335151 @default.
- W3091788260 cites W2113922914 @default.
- W3091788260 cites W2114700873 @default.
- W3091788260 cites W2125191493 @default.
- W3091788260 cites W2126419817 @default.
- W3091788260 cites W2130874433 @default.
- W3091788260 cites W2137015675 @default.
- W3091788260 cites W2137448659 @default.
- W3091788260 cites W2141165178 @default.
- W3091788260 cites W2141474572 @default.
- W3091788260 cites W2142678478 @default.
- W3091788260 cites W2146760000 @default.
- W3091788260 cites W2146821599 @default.
- W3091788260 cites W2149783843 @default.
- W3091788260 cites W2153491746 @default.
- W3091788260 cites W2155628349 @default.
- W3091788260 cites W2169669582 @default.
- W3091788260 cites W2181523240 @default.
- W3091788260 cites W2216234219 @default.
- W3091788260 cites W2510875395 @default.
- W3091788260 cites W2533755944 @default.
- W3091788260 cites W2602408874 @default.
- W3091788260 cites W2614142579 @default.
- W3091788260 cites W2799994822 @default.
- W3091788260 cites W2911390449 @default.
- W3091788260 cites W2964849163 @default.
- W3091788260 cites W2973719278 @default.
- W3091788260 cites W3031265420 @default.
- W3091788260 cites W3103145119 @default.
- W3091788260 cites W4211054902 @default.
- W3091788260 cites W4233582454 @default.
- W3091788260 cites W4236236547 @default.
- W3091788260 doi "https://doi.org/10.1101/2020.10.12.336362" @default.
- W3091788260 hasPublicationYear "2020" @default.
- W3091788260 type Work @default.
- W3091788260 sameAs 3091788260 @default.
- W3091788260 citedByCount "0" @default.
- W3091788260 crossrefType "posted-content" @default.
- W3091788260 hasAuthorship W3091788260A5009940856 @default.
- W3091788260 hasAuthorship W3091788260A5045315721 @default.
- W3091788260 hasAuthorship W3091788260A5072611345 @default.
- W3091788260 hasBestOaLocation W30917882601 @default.
- W3091788260 hasConcept C100299639 @default.
- W3091788260 hasConcept C104317684 @default.
- W3091788260 hasConcept C118346598 @default.
- W3091788260 hasConcept C141231307 @default.
- W3091788260 hasConcept C194993378 @default.
- W3091788260 hasConcept C2780855919 @default.
- W3091788260 hasConcept C40000846 @default.
- W3091788260 hasConcept C54355233 @default.
- W3091788260 hasConcept C54458228 @default.
- W3091788260 hasConcept C60542250 @default.
- W3091788260 hasConcept C64962909 @default.
- W3091788260 hasConcept C67705224 @default.
- W3091788260 hasConcept C73758832 @default.
- W3091788260 hasConcept C86803240 @default.
- W3091788260 hasConcept C94671646 @default.
- W3091788260 hasConcept C95444343 @default.
- W3091788260 hasConceptScore W3091788260C100299639 @default.
- W3091788260 hasConceptScore W3091788260C104317684 @default.
- W3091788260 hasConceptScore W3091788260C118346598 @default.
- W3091788260 hasConceptScore W3091788260C141231307 @default.
- W3091788260 hasConceptScore W3091788260C194993378 @default.
- W3091788260 hasConceptScore W3091788260C2780855919 @default.
- W3091788260 hasConceptScore W3091788260C40000846 @default.
- W3091788260 hasConceptScore W3091788260C54355233 @default.
- W3091788260 hasConceptScore W3091788260C54458228 @default.
- W3091788260 hasConceptScore W3091788260C60542250 @default.
- W3091788260 hasConceptScore W3091788260C64962909 @default.
- W3091788260 hasConceptScore W3091788260C67705224 @default.
- W3091788260 hasConceptScore W3091788260C73758832 @default.
- W3091788260 hasConceptScore W3091788260C86803240 @default.
- W3091788260 hasConceptScore W3091788260C94671646 @default.
- W3091788260 hasConceptScore W3091788260C95444343 @default.
- W3091788260 hasLocation W30917882601 @default.