Matches in SemOpenAlex for { <https://semopenalex.org/work/W3091887940> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W3091887940 endingPage "18" @default.
- W3091887940 startingPage "13" @default.
- W3091887940 abstract "Measurement of proteinuria in women with hypertensive disorders of pregnancy is of major importance in the diagnosis and management of preeclampsia. Urinary protein/creatinine ratio, which is commonly used to detect kidney damage in preeclampsia, suffers from important analytical limitations, including poor harmonization of results between laboratories. Adoption of albuminuria could help reduce interlaboratory bias, since methods used to quantify it are better harmonized. A total of 27 urinary samples collected from hypertensive women evaluated for preeclampsia were sent to four different clinical laboratories in Canada. Urinary proteins and albumin as well as urinary creatinine were measured in duplicates in one batch to calculate protein/creatinine (PCR) and albumin/creatinine (ACR) ratio. Statistical analyses were done to evaluate interlaboratory variability of urinary proteins and urinary albumin. Interlaboratory bias for urinary proteins ranged from 64.7% at low concentration to 3.9% at higher concentrations. In contrast, urinary albumin interlaboratory bias ranged from 29.2% to 4% from low to high concentrations. Coefficient of variation for urinary proteins reached a maximum of 91.5% in lower concentration while urinary albumin highest value was 42.7%. When looking at PCR and ACR ratio, eight samples had PCR measurement range that contained the diagnostic threshold used to detect kidney damage in HDP (30 mg/mmol), while only four samples had ACR ratio measurement range that contained the diagnostic threshold used outside of pregnancy in Canada (2 mg/mmol). Interlaboratory bias was lower for urinary albumin measurement compared to urinary proteins in hypertensive women evaluated for preeclampsia. Better harmonization with the use of albumin instead of protein measurement would reduce instances where results of different laboratories lead to opposite diagnosis of kidney damage in pregnancy." @default.
- W3091887940 created "2020-10-15" @default.
- W3091887940 creator A5012278873 @default.
- W3091887940 creator A5023600189 @default.
- W3091887940 creator A5064134078 @default.
- W3091887940 creator A5068219276 @default.
- W3091887940 creator A5076861258 @default.
- W3091887940 date "2021-01-01" @default.
- W3091887940 modified "2023-09-22" @default.
- W3091887940 title "Interlaboratory bias of albuminuria and proteinuria in hypertensive pregnancy" @default.
- W3091887940 cites W1963149371 @default.
- W3091887940 cites W1981818314 @default.
- W3091887940 cites W2001625933 @default.
- W3091887940 cites W2008921333 @default.
- W3091887940 cites W2064502040 @default.
- W3091887940 cites W2077173703 @default.
- W3091887940 cites W2077749968 @default.
- W3091887940 cites W2084967885 @default.
- W3091887940 cites W2092499299 @default.
- W3091887940 cites W2093954600 @default.
- W3091887940 cites W2129307901 @default.
- W3091887940 cites W2144554119 @default.
- W3091887940 cites W2161581547 @default.
- W3091887940 cites W2221015911 @default.
- W3091887940 cites W2260113709 @default.
- W3091887940 cites W2340460132 @default.
- W3091887940 cites W2412552091 @default.
- W3091887940 cites W2584676977 @default.
- W3091887940 cites W2766704154 @default.
- W3091887940 cites W2788072024 @default.
- W3091887940 cites W2964461836 @default.
- W3091887940 cites W3023969949 @default.
- W3091887940 doi "https://doi.org/10.1016/j.clinbiochem.2020.10.002" @default.
- W3091887940 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33031818" @default.
- W3091887940 hasPublicationYear "2021" @default.
- W3091887940 type Work @default.
- W3091887940 sameAs 3091887940 @default.
- W3091887940 citedByCount "1" @default.
- W3091887940 countsByYear W30918879402021 @default.
- W3091887940 crossrefType "journal-article" @default.
- W3091887940 hasAuthorship W3091887940A5012278873 @default.
- W3091887940 hasAuthorship W3091887940A5023600189 @default.
- W3091887940 hasAuthorship W3091887940A5064134078 @default.
- W3091887940 hasAuthorship W3091887940A5068219276 @default.
- W3091887940 hasAuthorship W3091887940A5076861258 @default.
- W3091887940 hasConcept C126322002 @default.
- W3091887940 hasConcept C126894567 @default.
- W3091887940 hasConcept C134018914 @default.
- W3091887940 hasConcept C159641895 @default.
- W3091887940 hasConcept C2776125364 @default.
- W3091887940 hasConcept C2776174234 @default.
- W3091887940 hasConcept C2777218350 @default.
- W3091887940 hasConcept C2779234561 @default.
- W3091887940 hasConcept C2779561371 @default.
- W3091887940 hasConcept C2780026642 @default.
- W3091887940 hasConcept C2780091579 @default.
- W3091887940 hasConcept C2780306776 @default.
- W3091887940 hasConcept C54355233 @default.
- W3091887940 hasConcept C71924100 @default.
- W3091887940 hasConcept C77411442 @default.
- W3091887940 hasConcept C86803240 @default.
- W3091887940 hasConceptScore W3091887940C126322002 @default.
- W3091887940 hasConceptScore W3091887940C126894567 @default.
- W3091887940 hasConceptScore W3091887940C134018914 @default.
- W3091887940 hasConceptScore W3091887940C159641895 @default.
- W3091887940 hasConceptScore W3091887940C2776125364 @default.
- W3091887940 hasConceptScore W3091887940C2776174234 @default.
- W3091887940 hasConceptScore W3091887940C2777218350 @default.
- W3091887940 hasConceptScore W3091887940C2779234561 @default.
- W3091887940 hasConceptScore W3091887940C2779561371 @default.
- W3091887940 hasConceptScore W3091887940C2780026642 @default.
- W3091887940 hasConceptScore W3091887940C2780091579 @default.
- W3091887940 hasConceptScore W3091887940C2780306776 @default.
- W3091887940 hasConceptScore W3091887940C54355233 @default.
- W3091887940 hasConceptScore W3091887940C71924100 @default.
- W3091887940 hasConceptScore W3091887940C77411442 @default.
- W3091887940 hasConceptScore W3091887940C86803240 @default.
- W3091887940 hasFunder F4320334506 @default.
- W3091887940 hasLocation W30918879401 @default.
- W3091887940 hasOpenAccess W3091887940 @default.
- W3091887940 hasPrimaryLocation W30918879401 @default.
- W3091887940 hasRelatedWork W13715332 @default.
- W3091887940 hasRelatedWork W17209738 @default.
- W3091887940 hasRelatedWork W19920308 @default.
- W3091887940 hasRelatedWork W20195804 @default.
- W3091887940 hasRelatedWork W220526 @default.
- W3091887940 hasRelatedWork W4842688 @default.
- W3091887940 hasRelatedWork W6633122 @default.
- W3091887940 hasRelatedWork W679746 @default.
- W3091887940 hasRelatedWork W9077844 @default.
- W3091887940 hasRelatedWork W18847964 @default.
- W3091887940 hasVolume "87" @default.
- W3091887940 isParatext "false" @default.
- W3091887940 isRetracted "false" @default.
- W3091887940 magId "3091887940" @default.
- W3091887940 workType "article" @default.