Matches in SemOpenAlex for { <https://semopenalex.org/work/W3091904978> ?p ?o ?g. }
- W3091904978 endingPage "34" @default.
- W3091904978 startingPage "23" @default.
- W3091904978 abstract "The aim of this study was to examine the indirect burden of employed multiple sclerosis (MS) patients initiating disease-modifying therapies (DMTs) in the US. DMT-treated MS patients (DMT users) and direct-matched controls without MS (1:3) were captured using the IBM MarketScan Commercial Claims and Encounters Database and the Health and Productivity Management Database between 1 January 2009 and 1 January 2017. DMT users were also stratified by route of administration. Time loss and costs from absenteeism, short-term disability, and long-term disability were assessed for DMT users and matched controls. A total of 3022 DMT users were matched to 9066 controls. Compared with injectable DMT users, oral DMT users took twice as long to initiate therapy but had numerically lower absenteeism costs and significantly lower long-term disability costs in the first year after DMT initiation. The mean (standard deviation) indirect costs of absenteeism, short-term disability, and long-term disability were US$6474 (US$6779), US$2368 (US$5777), and US$280 (US$2578), respectively, for DMT users and US$4468 (US$3814), US$328 (US$1950), and US$36 (US$938), respectively, for controls in the first year (all p < 0.001). Employed DMT users in the US incurred incremental increased indirect burden ($2007 in absenteeism, $2040 in short-term disability, and $244 in long-term disability) compared with matched controls. Despite evidence of delays in treatment initiation, oral DMT users had evidence of reduced work loss compared with injectable users, suggesting that open access to all treatment options may reduce the indirect burden of MS. Additional research into the impact of route of administration on the burden of long-term disability among MS patients is needed." @default.
- W3091904978 created "2020-10-15" @default.
- W3091904978 creator A5027620562 @default.
- W3091904978 creator A5043289431 @default.
- W3091904978 creator A5052830655 @default.
- W3091904978 creator A5060985600 @default.
- W3091904978 creator A5069726595 @default.
- W3091904978 creator A5078134055 @default.
- W3091904978 creator A5087228307 @default.
- W3091904978 date "2020-10-13" @default.
- W3091904978 modified "2023-09-27" @default.
- W3091904978 title "Productivity Loss and Associated Costs Among Employed Patients Receiving Disease-Modifying Treatment for Multiple Sclerosis" @default.
- W3091904978 cites W1974000699 @default.
- W3091904978 cites W1979374594 @default.
- W3091904978 cites W1997817922 @default.
- W3091904978 cites W2014094373 @default.
- W3091904978 cites W2022502930 @default.
- W3091904978 cites W2034896241 @default.
- W3091904978 cites W2049566645 @default.
- W3091904978 cites W2060605559 @default.
- W3091904978 cites W2067673653 @default.
- W3091904978 cites W2105206040 @default.
- W3091904978 cites W2123061840 @default.
- W3091904978 cites W2125279751 @default.
- W3091904978 cites W2131902490 @default.
- W3091904978 cites W2133755641 @default.
- W3091904978 cites W2136981251 @default.
- W3091904978 cites W2169394319 @default.
- W3091904978 cites W2176165150 @default.
- W3091904978 cites W2192794573 @default.
- W3091904978 cites W2503426394 @default.
- W3091904978 cites W2506374602 @default.
- W3091904978 cites W2525708074 @default.
- W3091904978 cites W2560929962 @default.
- W3091904978 cites W2608396028 @default.
- W3091904978 cites W2753435506 @default.
- W3091904978 cites W2777074421 @default.
- W3091904978 cites W2800924304 @default.
- W3091904978 cites W2807755883 @default.
- W3091904978 cites W2883900986 @default.
- W3091904978 cites W2911658427 @default.
- W3091904978 cites W4319308236 @default.
- W3091904978 doi "https://doi.org/10.1007/s41669-020-00233-8" @default.
- W3091904978 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7895882" @default.
- W3091904978 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33051856" @default.
- W3091904978 hasPublicationYear "2020" @default.
- W3091904978 type Work @default.
- W3091904978 sameAs 3091904978 @default.
- W3091904978 citedByCount "4" @default.
- W3091904978 countsByYear W30919049782020 @default.
- W3091904978 countsByYear W30919049782022 @default.
- W3091904978 countsByYear W30919049782023 @default.
- W3091904978 crossrefType "journal-article" @default.
- W3091904978 hasAuthorship W3091904978A5027620562 @default.
- W3091904978 hasAuthorship W3091904978A5043289431 @default.
- W3091904978 hasAuthorship W3091904978A5052830655 @default.
- W3091904978 hasAuthorship W3091904978A5060985600 @default.
- W3091904978 hasAuthorship W3091904978A5069726595 @default.
- W3091904978 hasAuthorship W3091904978A5078134055 @default.
- W3091904978 hasAuthorship W3091904978A5087228307 @default.
- W3091904978 hasBestOaLocation W30919049781 @default.
- W3091904978 hasConcept C121955636 @default.
- W3091904978 hasConcept C139719470 @default.
- W3091904978 hasConcept C144133560 @default.
- W3091904978 hasConcept C15744967 @default.
- W3091904978 hasConcept C162324750 @default.
- W3091904978 hasConcept C1862650 @default.
- W3091904978 hasConcept C204983608 @default.
- W3091904978 hasConcept C27400517 @default.
- W3091904978 hasConcept C6964187 @default.
- W3091904978 hasConcept C71924100 @default.
- W3091904978 hasConcept C77805123 @default.
- W3091904978 hasConceptScore W3091904978C121955636 @default.
- W3091904978 hasConceptScore W3091904978C139719470 @default.
- W3091904978 hasConceptScore W3091904978C144133560 @default.
- W3091904978 hasConceptScore W3091904978C15744967 @default.
- W3091904978 hasConceptScore W3091904978C162324750 @default.
- W3091904978 hasConceptScore W3091904978C1862650 @default.
- W3091904978 hasConceptScore W3091904978C204983608 @default.
- W3091904978 hasConceptScore W3091904978C27400517 @default.
- W3091904978 hasConceptScore W3091904978C6964187 @default.
- W3091904978 hasConceptScore W3091904978C71924100 @default.
- W3091904978 hasConceptScore W3091904978C77805123 @default.
- W3091904978 hasIssue "1" @default.
- W3091904978 hasLocation W30919049781 @default.
- W3091904978 hasLocation W30919049782 @default.
- W3091904978 hasOpenAccess W3091904978 @default.
- W3091904978 hasPrimaryLocation W30919049781 @default.
- W3091904978 hasRelatedWork W146066859 @default.
- W3091904978 hasRelatedWork W1511323177 @default.
- W3091904978 hasRelatedWork W2036341666 @default.
- W3091904978 hasRelatedWork W2075394416 @default.
- W3091904978 hasRelatedWork W2075773226 @default.
- W3091904978 hasRelatedWork W2345642662 @default.
- W3091904978 hasRelatedWork W2781747277 @default.
- W3091904978 hasRelatedWork W3007439706 @default.
- W3091904978 hasRelatedWork W3167361784 @default.
- W3091904978 hasRelatedWork W3139906773 @default.