Matches in SemOpenAlex for { <https://semopenalex.org/work/W3091925350> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W3091925350 abstract "The aim of this study was to determine plasma adropin concentration and parameters of insulin resistance in obese male type 2 diabetes mellitus (T2DM) patients before and after 3-month liraglutide treatment. In this interventional study, we enrolled 15 obese male T2DM patients with body mass index (BMI) >35 kg/m2, uncontrolled disease and HbA1c >7.5%, having previously taken taking two oral antidiabetic drugs. We modified their therapy to metformin and liraglutide for the next three months. After three months of liraglutide treatment, we observed significant decrease in body weight (from 111.5±18.7 kg to 109.2±17.5 kg, p=0.016) and BMI (from 40.9±7.3 to 40.1±7.0 kg/m2, p=0.021). Plasma adropin concentration increased significantly (p=0.003) compared with baseline. Fasting plasma insulin level decreased from 17.79±6.53 to 13.38±3.51 mU/L (p=0.002), fasting plasma glucose level decreased from 8.66±3.07 to 7.41±2.21 mmol/L (p=0.004) and HbA1c decreased from 7.98±0.70% to 7.26±0.36% (p=0.003). Insulin resistance presented as HOMA-IR decreased significantly from 7.30±5.19 to 4.52±2.61 (p=0.002). Systolic blood pressure, lipid status, liver and kidney function improved, but not reaching statistical significance. Treating obese male T2DM patients with liraglutide resulted in a significantly higher plasma adropin concentration, significant weight loss and improved parameters of insulin resistance, i.e. decreased fasting plasma insulin, plasma glucose levels and HOMA-IR." @default.
- W3091925350 created "2020-10-15" @default.
- W3091925350 creator A5077774950 @default.
- W3091925350 date "2020-01-01" @default.
- W3091925350 modified "2023-09-25" @default.
- W3091925350 title "Adropin – Potential Link in Cardiovascular Protection for Obese Male Type 2 Diabetes Mellitus Patients Treated with Liraglutide" @default.
- W3091925350 cites W126987257 @default.
- W3091925350 cites W1967256054 @default.
- W3091925350 cites W1972697162 @default.
- W3091925350 cites W1978191819 @default.
- W3091925350 cites W1985482823 @default.
- W3091925350 cites W2006359998 @default.
- W3091925350 cites W2014520461 @default.
- W3091925350 cites W2016470916 @default.
- W3091925350 cites W2019141360 @default.
- W3091925350 cites W2028009073 @default.
- W3091925350 cites W2033185429 @default.
- W3091925350 cites W2057651652 @default.
- W3091925350 cites W2081283952 @default.
- W3091925350 cites W2083451552 @default.
- W3091925350 cites W2086087714 @default.
- W3091925350 cites W2086177834 @default.
- W3091925350 cites W2097226721 @default.
- W3091925350 cites W2110333911 @default.
- W3091925350 cites W2127294907 @default.
- W3091925350 cites W2134099620 @default.
- W3091925350 cites W2138290933 @default.
- W3091925350 cites W2147091345 @default.
- W3091925350 cites W2194536288 @default.
- W3091925350 cites W2425644022 @default.
- W3091925350 cites W24762309 @default.
- W3091925350 cites W2518656207 @default.
- W3091925350 cites W2791011305 @default.
- W3091925350 cites W2801866309 @default.
- W3091925350 cites W2802115148 @default.
- W3091925350 cites W2883899157 @default.
- W3091925350 cites W2971618362 @default.
- W3091925350 doi "https://doi.org/10.20471/acc.2020.59.02.19" @default.
- W3091925350 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7808222" @default.
- W3091925350 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33456123" @default.
- W3091925350 hasPublicationYear "2020" @default.
- W3091925350 type Work @default.
- W3091925350 sameAs 3091925350 @default.
- W3091925350 citedByCount "12" @default.
- W3091925350 countsByYear W30919253502021 @default.
- W3091925350 countsByYear W30919253502022 @default.
- W3091925350 countsByYear W30919253502023 @default.
- W3091925350 crossrefType "journal-article" @default.
- W3091925350 hasAuthorship W3091925350A5077774950 @default.
- W3091925350 hasBestOaLocation W30919253501 @default.
- W3091925350 hasConcept C114614502 @default.
- W3091925350 hasConcept C126322002 @default.
- W3091925350 hasConcept C134018914 @default.
- W3091925350 hasConcept C2777180221 @default.
- W3091925350 hasConcept C2778753846 @default.
- W3091925350 hasConcept C2781308992 @default.
- W3091925350 hasConcept C2910068830 @default.
- W3091925350 hasConcept C33923547 @default.
- W3091925350 hasConcept C555293320 @default.
- W3091925350 hasConcept C71924100 @default.
- W3091925350 hasConceptScore W3091925350C114614502 @default.
- W3091925350 hasConceptScore W3091925350C126322002 @default.
- W3091925350 hasConceptScore W3091925350C134018914 @default.
- W3091925350 hasConceptScore W3091925350C2777180221 @default.
- W3091925350 hasConceptScore W3091925350C2778753846 @default.
- W3091925350 hasConceptScore W3091925350C2781308992 @default.
- W3091925350 hasConceptScore W3091925350C2910068830 @default.
- W3091925350 hasConceptScore W3091925350C33923547 @default.
- W3091925350 hasConceptScore W3091925350C555293320 @default.
- W3091925350 hasConceptScore W3091925350C71924100 @default.
- W3091925350 hasLocation W30919253501 @default.
- W3091925350 hasLocation W30919253502 @default.
- W3091925350 hasOpenAccess W3091925350 @default.
- W3091925350 hasPrimaryLocation W30919253501 @default.
- W3091925350 hasRelatedWork W1966504330 @default.
- W3091925350 hasRelatedWork W1979139803 @default.
- W3091925350 hasRelatedWork W2030889776 @default.
- W3091925350 hasRelatedWork W2037631372 @default.
- W3091925350 hasRelatedWork W2040058909 @default.
- W3091925350 hasRelatedWork W2132898409 @default.
- W3091925350 hasRelatedWork W2133122377 @default.
- W3091925350 hasRelatedWork W2748952813 @default.
- W3091925350 hasRelatedWork W2944172663 @default.
- W3091925350 hasRelatedWork W4289199699 @default.
- W3091925350 isParatext "false" @default.
- W3091925350 isRetracted "false" @default.
- W3091925350 magId "3091925350" @default.
- W3091925350 workType "article" @default.