FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3091937757> ?p ?o ?g. }

• W3091937757 endingPage "2046" @default.
• W3091937757 startingPage "2037" @default.
• W3091937757 abstract "Severe preeclampsia may affect placental development, and high homocysteine (Hcy) levels are linked to intellectual disability. However, the correlation between perinatal Hcy levels and intellectual ability remains unknown in severe preeclampsia-affected offspring.We aimed to investigate the intellectual ability in offspring born from preeclamptic mothers and examine the role of prenatal Hcy in the prediction of intellectual disability in preschool-aged offspring.The IQ scores were compared between 101 children born to mothers with severe preeclampsia and 202 offsprings born to normotensive mothers. Maternal Hcy levels within 7 days prior to delivery and postnatal cord blood Hcy were measured. The associations of Hcy with IQ scores were evaluated, and the optimal cut-off values for predicting intellectual disability in the offspring were estimated.The children born to mothers with severe preeclampsia had a greater postnatal cord blood Hcy than those born from normotensive mothers (P < 0.001), and the mothers with severe preeclampsia presented a higher prenatal Hcy (P < 0.001). The children born to mothers with severe preeclampsia had significantly lower IQ scores than those born from normotensive mothers, and a higher Hcy was associated with a lower IQ in preeclampsia-affected offspring. The prevalence of intellectual disability was 2.86 times higher in severe preeclampsia-affected offspring than in children born from normotensive mothers, and the prevalence of low IQ was greater in children born to mothers with severe preeclampsia than in those from normotensive mothers. ROC curve analysis showed that both maternal and cord blood Hcy were predictors of intellectual disability, and the optimal cut-off for predicting intellectual disability was 17.7 and 9.75 μmol/L for maternal and cord blood Hcy.Perinatal exposure to severe preeclampsia has an adverse effect on postnatal intellectual development, and high maternal and cord blood Hcy may contribute to this association." @default.
• W3091937757 created "2020-10-15" @default.
• W3091937757 creator A5010360573 @default.
• W3091937757 creator A5024999301 @default.
• W3091937757 creator A5028173741 @default.
• W3091937757 creator A5034671229 @default.
• W3091937757 creator A5052432001 @default.
• W3091937757 creator A5067847652 @default.
• W3091937757 creator A5076618609 @default.
• W3091937757 creator A5080426038 @default.
• W3091937757 creator A5083509058 @default.
• W3091937757 creator A5087100048 @default.
• W3091937757 date "2020-10-01" @default.
• W3091937757 modified "2023-09-24" @default.
• W3091937757 title "<p>Reduced Intellectual Ability in Offspring Born from Preeclamptic Mothers: A Prospective Cohort Study</p>" @default.
• W3091937757 cites W1501771384 @default.
• W3091937757 cites W1838358999 @default.
• W3091937757 cites W1923441758 @default.
• W3091937757 cites W1923791448 @default.
• W3091937757 cites W1966292733 @default.
• W3091937757 cites W1978940943 @default.
• W3091937757 cites W1987110992 @default.
• W3091937757 cites W1993145269 @default.
• W3091937757 cites W2025961381 @default.
• W3091937757 cites W2035797009 @default.
• W3091937757 cites W2039068497 @default.
• W3091937757 cites W2046222258 @default.
• W3091937757 cites W2048159483 @default.
• W3091937757 cites W2059873008 @default.
• W3091937757 cites W2061506872 @default.
• W3091937757 cites W2066520484 @default.
• W3091937757 cites W2075555698 @default.
• W3091937757 cites W2092155853 @default.
• W3091937757 cites W2127266105 @default.
• W3091937757 cites W2144594833 @default.
• W3091937757 cites W2203006631 @default.
• W3091937757 cites W2267105515 @default.
• W3091937757 cites W2286986001 @default.
• W3091937757 cites W2304792647 @default.
• W3091937757 cites W2333718794 @default.
• W3091937757 cites W2394989810 @default.
• W3091937757 cites W2415616035 @default.
• W3091937757 cites W2417496748 @default.
• W3091937757 cites W2555066822 @default.
• W3091937757 cites W2612469592 @default.
• W3091937757 cites W2746176044 @default.
• W3091937757 cites W2805841809 @default.
• W3091937757 cites W2807447863 @default.
• W3091937757 cites W2809087508 @default.
• W3091937757 cites W2884220660 @default.
• W3091937757 cites W2895907236 @default.
• W3091937757 cites W2901867525 @default.
• W3091937757 cites W2916697167 @default.
• W3091937757 cites W2935104625 @default.
• W3091937757 cites W2966621528 @default.
• W3091937757 cites W2971283705 @default.
• W3091937757 cites W2974179005 @default.
• W3091937757 cites W2996396325 @default.
• W3091937757 cites W4211203631 @default.
• W3091937757 cites W4229534512 @default.
• W3091937757 cites W4238038302 @default.
• W3091937757 cites W4377865106 @default.
• W3091937757 doi "https://doi.org/10.2147/rmhp.s277521" @default.
• W3091937757 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7549660" @default.
• W3091937757 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33116984" @default.
• W3091937757 hasPublicationYear "2020" @default.
• W3091937757 type Work @default.
• W3091937757 sameAs 3091937757 @default.
• W3091937757 citedByCount "2" @default.
• W3091937757 countsByYear W30919377572021 @default.
• W3091937757 crossrefType "journal-article" @default.
• W3091937757 hasAuthorship W3091937757A5010360573 @default.
• W3091937757 hasAuthorship W3091937757A5024999301 @default.
• W3091937757 hasAuthorship W3091937757A5028173741 @default.
• W3091937757 hasAuthorship W3091937757A5034671229 @default.
• W3091937757 hasAuthorship W3091937757A5052432001 @default.
• W3091937757 hasAuthorship W3091937757A5067847652 @default.
• W3091937757 hasAuthorship W3091937757A5076618609 @default.
• W3091937757 hasAuthorship W3091937757A5080426038 @default.
• W3091937757 hasAuthorship W3091937757A5083509058 @default.
• W3091937757 hasAuthorship W3091937757A5087100048 @default.
• W3091937757 hasBestOaLocation W30919377571 @default.
• W3091937757 hasConcept C112672928 @default.
• W3091937757 hasConcept C118552586 @default.
• W3091937757 hasConcept C126322002 @default.
• W3091937757 hasConcept C131872663 @default.
• W3091937757 hasConcept C172680121 @default.
• W3091937757 hasConcept C187212893 @default.
• W3091937757 hasConcept C188816634 @default.
• W3091937757 hasConcept C201903717 @default.
• W3091937757 hasConcept C2777218350 @default.
• W3091937757 hasConcept C2779234561 @default.
• W3091937757 hasConcept C2780914630 @default.
• W3091937757 hasConcept C54355233 @default.
• W3091937757 hasConcept C551499885 @default.
• W3091937757 hasConcept C71924100 @default.
• W3091937757 hasConcept C72563966 @default.
• W3091937757 hasConcept C86803240 @default.

• next