Matches in SemOpenAlex for { <https://semopenalex.org/work/W3091956242> ?p ?o ?g. }
- W3091956242 endingPage "e121" @default.
- W3091956242 startingPage "e121" @default.
- W3091956242 abstract "Abstract Recent advances in metagenomic sequencing have enabled discovery of diverse, distinct microbes and viruses. Bacteriophages, the most abundant biological entity on Earth, evolve rapidly, and therefore, detection of unknown bacteriophages in sequence datasets is a challenge. Most of the existing detection methods rely on sequence similarity to known bacteriophage sequences, impeding the identification and characterization of distinct, highly divergent bacteriophage families. Here we present Seeker, a deep-learning tool for alignment-free identification of phage sequences. Seeker allows rapid detection of phages in sequence datasets and differentiation of phage sequences from bacterial ones, even when those phages exhibit little sequence similarity to established phage families. We comprehensively validate Seeker's ability to identify previously unidentified phages, and employ this method to detect unknown phages, some of which are highly divergent from the known phage families. We provide a web portal (seeker.pythonanywhere.com) and a user-friendly Python package (github.com/gussow/seeker) allowing researchers to easily apply Seeker in metagenomic studies, for the detection of diverse unknown bacteriophages." @default.
- W3091956242 created "2020-10-15" @default.
- W3091956242 creator A5020874644 @default.
- W3091956242 creator A5035240489 @default.
- W3091956242 creator A5050344026 @default.
- W3091956242 creator A5056116719 @default.
- W3091956242 creator A5064925165 @default.
- W3091956242 date "2020-10-12" @default.
- W3091956242 modified "2023-10-11" @default.
- W3091956242 title "Seeker: alignment-free identification of bacteriophage genomes by deep learning" @default.
- W3091956242 cites W1519820746 @default.
- W3091956242 cites W1757675837 @default.
- W3091956242 cites W1967239919 @default.
- W3091956242 cites W1991604124 @default.
- W3091956242 cites W1995320511 @default.
- W3091956242 cites W2035793410 @default.
- W3091956242 cites W2051210555 @default.
- W3091956242 cites W2059029000 @default.
- W3091956242 cites W2064675550 @default.
- W3091956242 cites W2068687524 @default.
- W3091956242 cites W2081319466 @default.
- W3091956242 cites W2084814249 @default.
- W3091956242 cites W2098132478 @default.
- W3091956242 cites W2100363512 @default.
- W3091956242 cites W2105329815 @default.
- W3091956242 cites W2119859604 @default.
- W3091956242 cites W2126317009 @default.
- W3091956242 cites W2130124027 @default.
- W3091956242 cites W2132926880 @default.
- W3091956242 cites W2138411980 @default.
- W3091956242 cites W2141394464 @default.
- W3091956242 cites W2143485490 @default.
- W3091956242 cites W2149429041 @default.
- W3091956242 cites W2154556219 @default.
- W3091956242 cites W2158406706 @default.
- W3091956242 cites W2158714788 @default.
- W3091956242 cites W2173732482 @default.
- W3091956242 cites W2293634267 @default.
- W3091956242 cites W2296073425 @default.
- W3091956242 cites W2321452352 @default.
- W3091956242 cites W2345791363 @default.
- W3091956242 cites W2473329891 @default.
- W3091956242 cites W2545536333 @default.
- W3091956242 cites W2562468253 @default.
- W3091956242 cites W2597036303 @default.
- W3091956242 cites W2732139758 @default.
- W3091956242 cites W2797413896 @default.
- W3091956242 cites W2803013275 @default.
- W3091956242 cites W2935703330 @default.
- W3091956242 cites W2949831026 @default.
- W3091956242 cites W2950954328 @default.
- W3091956242 cites W2991012415 @default.
- W3091956242 cites W3003110834 @default.
- W3091956242 cites W3033129278 @default.
- W3091956242 cites W4211141369 @default.
- W3091956242 cites W4211164325 @default.
- W3091956242 cites W4239871258 @default.
- W3091956242 doi "https://doi.org/10.1093/nar/gkaa856" @default.
- W3091956242 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7708075" @default.
- W3091956242 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33045744" @default.
- W3091956242 hasPublicationYear "2020" @default.
- W3091956242 type Work @default.
- W3091956242 sameAs 3091956242 @default.
- W3091956242 citedByCount "63" @default.
- W3091956242 countsByYear W30919562422021 @default.
- W3091956242 countsByYear W30919562422022 @default.
- W3091956242 countsByYear W30919562422023 @default.
- W3091956242 crossrefType "journal-article" @default.
- W3091956242 hasAuthorship W3091956242A5020874644 @default.
- W3091956242 hasAuthorship W3091956242A5035240489 @default.
- W3091956242 hasAuthorship W3091956242A5050344026 @default.
- W3091956242 hasAuthorship W3091956242A5056116719 @default.
- W3091956242 hasAuthorship W3091956242A5064925165 @default.
- W3091956242 hasBestOaLocation W30919562421 @default.
- W3091956242 hasConcept C104317684 @default.
- W3091956242 hasConcept C111919701 @default.
- W3091956242 hasConcept C116834253 @default.
- W3091956242 hasConcept C141231307 @default.
- W3091956242 hasConcept C15151743 @default.
- W3091956242 hasConcept C190743605 @default.
- W3091956242 hasConcept C2776441376 @default.
- W3091956242 hasConcept C2778112365 @default.
- W3091956242 hasConcept C41008148 @default.
- W3091956242 hasConcept C51679486 @default.
- W3091956242 hasConcept C519991488 @default.
- W3091956242 hasConcept C54355233 @default.
- W3091956242 hasConcept C547475151 @default.
- W3091956242 hasConcept C59822182 @default.
- W3091956242 hasConcept C70721500 @default.
- W3091956242 hasConcept C86803240 @default.
- W3091956242 hasConceptScore W3091956242C104317684 @default.
- W3091956242 hasConceptScore W3091956242C111919701 @default.
- W3091956242 hasConceptScore W3091956242C116834253 @default.
- W3091956242 hasConceptScore W3091956242C141231307 @default.
- W3091956242 hasConceptScore W3091956242C15151743 @default.
- W3091956242 hasConceptScore W3091956242C190743605 @default.
- W3091956242 hasConceptScore W3091956242C2776441376 @default.
- W3091956242 hasConceptScore W3091956242C2778112365 @default.