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• W3092081291 abstract "Abstract Context Nutritional interventions stimulate muscle protein synthesis in older adults. To optimize muscle mass preservation and gains, several factors, including type, dose, frequency, timing, duration, and adherence have to be considered. Objective This systematic review and meta-analysis aimed to summarize these factors influencing the efficacy of nutritional interventions on muscle mass in older adults. Data Sources A systematic search was performed using the electronic databases MEDLINE, Embase, CINAHL, Cochrane Central Register of Controlled Trials, and SPORTDiscus from inception date to November 22, 2017, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Inclusion criteria included randomized controlled trials, mean or median age ≥65 years, and reporting muscle mass at baseline and postintervention. Exclusion criteria included genetically inherited diseases, anabolic drugs or hormone therapies, neuromuscular electrical stimulation, chronic kidney disease, kidney failure, neuromuscular disorders, and cancer. Data Extraction Extracted data included study characteristics (ie, population, sample size, age, sex), muscle mass measurements (ie, method, measure, unit), effect of the intervention vs the control group, and nutritional intervention factors (ie, type, composition, dose, duration, frequency, timing, and adherence). Data Analysis Standardized mean differences and 95%CIs were calculated from baseline to postintervention. A meta-analysis was performed using a random-effects model and grouped by the type of intervention. Conclusions Twenty-nine studies were included, encompassing 2255 participants (mean age, 78.1 years; SD, 2.22). Amino acids, creatine, β-hydroxy-β-methylbutyrate, and protein with amino acids supplementation significantly improved muscle mass. No effect was found for protein supplementation alone, protein and other components, and polyunsaturated fatty acids. High interstudy variability was observed regarding the dose, duration, and frequency, coupled with inconsistency in reporting timing and adherence. Overall, several nutritional interventions could be effective to improve muscle mass measures in older adults. Because of the substantial variability of the intervention factors among studies, the optimum profile is yet to be established. Systematic Review Registration PROSPERO registration no. CRD42018111306." @default.
• W3092081291 created "2020-10-15" @default.
• W3092081291 creator A5015665688 @default.
• W3092081291 creator A5020166851 @default.
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• W3092081291 date "2020-10-08" @default.
• W3092081291 modified "2023-10-18" @default.
• W3092081291 title "Factors influencing the efficacy of nutritional interventions on muscle mass in older adults: a systematic review and meta-analysis" @default.
• W3092081291 cites W139939634 @default.
• W3092081291 cites W1508614814 @default.
• W3092081291 cites W1782094909 @default.
• W3092081291 cites W1820460245 @default.
• W3092081291 cites W1858598969 @default.
• W3092081291 cites W1896545285 @default.
• W3092081291 cites W1904967490 @default.
• W3092081291 cites W1916081948 @default.
• W3092081291 cites W1967783577 @default.
• W3092081291 cites W1975527464 @default.
• W3092081291 cites W1977289844 @default.
• W3092081291 cites W1977506726 @default.
• W3092081291 cites W1978097115 @default.
• W3092081291 cites W1992328832 @default.
• W3092081291 cites W1998432767 @default.
• W3092081291 cites W2000532682 @default.
• W3092081291 cites W2002862490 @default.
• W3092081291 cites W2007789681 @default.
• W3092081291 cites W2021653273 @default.
• W3092081291 cites W2022188251 @default.
• W3092081291 cites W2022928755 @default.
• W3092081291 cites W2029230411 @default.
• W3092081291 cites W2039735127 @default.
• W3092081291 cites W2047699089 @default.
• W3092081291 cites W2047767140 @default.
• W3092081291 cites W2056891285 @default.
• W3092081291 cites W2064957965 @default.
• W3092081291 cites W2065285042 @default.
• W3092081291 cites W2073702544 @default.
• W3092081291 cites W2086677650 @default.
• W3092081291 cites W2087071981 @default.
• W3092081291 cites W2087657684 @default.
• W3092081291 cites W2094332493 @default.
• W3092081291 cites W2098866396 @default.
• W3092081291 cites W2098923148 @default.
• W3092081291 cites W2102902846 @default.
• W3092081291 cites W2104357394 @default.
• W3092081291 cites W2104371315 @default.
• W3092081291 cites W2105721976 @default.
• W3092081291 cites W2109887283 @default.
• W3092081291 cites W2110630734 @default.
• W3092081291 cites W2111942374 @default.
• W3092081291 cites W2116706114 @default.
• W3092081291 cites W2121168414 @default.
• W3092081291 cites W2122615082 @default.
• W3092081291 cites W2124503813 @default.
• W3092081291 cites W2126265811 @default.
• W3092081291 cites W2127130842 @default.
• W3092081291 cites W2129894754 @default.
• W3092081291 cites W2133222708 @default.
• W3092081291 cites W2145555293 @default.
• W3092081291 cites W2148428406 @default.
• W3092081291 cites W2158574059 @default.
• W3092081291 cites W2163921565 @default.
• W3092081291 cites W2167013734 @default.
• W3092081291 cites W2172570273 @default.
• W3092081291 cites W2177553561 @default.
• W3092081291 cites W2217782636 @default.
• W3092081291 cites W2222487754 @default.
• W3092081291 cites W2299538125 @default.
• W3092081291 cites W2326230104 @default.
• W3092081291 cites W2413534694 @default.
• W3092081291 cites W2520038786 @default.
• W3092081291 cites W2522933482 @default.
• W3092081291 cites W2534399581 @default.
• W3092081291 cites W2537831197 @default.
• W3092081291 cites W2576803076 @default.
• W3092081291 cites W2587167574 @default.
• W3092081291 cites W2593764183 @default.
• W3092081291 cites W2600323744 @default.
• W3092081291 cites W2617764165 @default.
• W3092081291 cites W2624479585 @default.
• W3092081291 cites W2738670508 @default.
• W3092081291 cites W2746088396 @default.
• W3092081291 cites W2747357561 @default.
• W3092081291 cites W2748094183 @default.
• W3092081291 cites W2759898354 @default.
• W3092081291 cites W2765246109 @default.
• W3092081291 cites W2765375372 @default.
• W3092081291 cites W2783113045 @default.
• W3092081291 cites W2791274003 @default.
• W3092081291 cites W2802809976 @default.
• W3092081291 cites W2887002797 @default.
• W3092081291 cites W2887218535 @default.
• W3092081291 cites W2897513125 @default.
• W3092081291 cites W2900982893 @default.
• W3092081291 cites W2901144022 @default.
• W3092081291 cites W2901294932 @default.
• W3092081291 cites W2915119994 @default.

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