FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3092121036> ?p ?o ?g. }

• W3092121036 endingPage "110790" @default.
• W3092121036 startingPage "110790" @default.
• W3092121036 abstract "This study investigated the in vitro effect of various vital dyes in common clinical use on human Müller cell viability, and it compared the toxicity of these dyes using a cell culture model. Müller cells were exposed to a series of concentrations (1 %, 0.5 %, 0.25 %, and 0.125 % or 12.9 mM, 6.45 mM, 3.22 mM and 1.61 mM) of Indocyanine green (ICG) for 2, 24, 48, and 72 h. Similarly, groups of Müller cells were stained with “Heavy” brilliant blue G (HBBG), Trypan blue (TB) (0.15 %, or 1.56 mM), Membrane-blue-dual (MBD), and ICG (0.25 %, or 3.22 mM) or BBG (0.025 %, or 0.3 mM) with glucose (GS) (50 %, 66 % and 75 % or 2.78 M, 3.67 M and 4.17 M) for 30, 60, and 120 s. Cell viability was measured with the Cell Counting Kit-8 (CCK-8) and Lactate Dehydrogenase (LDH) release assays. We found that high stain concentration and long exposure time resulted in increased toxicity to Müller cells. Nevertheless, ICG seemed to be safe at the clinically relevant concentration of 0.25 % (3.22 mM) in the short time of exposure. TB was safer than both HBBG and MBD, especially HBBG. Hypertonic GS as a dilution was not safe for Müller cells, and the negative effect was more obvious in 0.025 % (0.3 mM) BBG than that in 0.25 % (3.22 mM) ICG. This is the first report to observe the cytotoxicity of commonly used stains in clinical on human Müller cells in vitro, and to provide some basis for further studies, including in vivo investigation." @default.
• W3092121036 created "2020-10-15" @default.
• W3092121036 creator A5022681943 @default.
• W3092121036 creator A5035229031 @default.
• W3092121036 creator A5054579471 @default.
• W3092121036 creator A5084361475 @default.
• W3092121036 date "2020-12-01" @default.
• W3092121036 modified "2023-09-25" @default.
• W3092121036 title "Comparative effects of commonly used intraocular dyes on the viability of human retina Müller cells" @default.
• W3092121036 cites W115223116 @default.
• W3092121036 cites W154447721 @default.
• W3092121036 cites W1965891729 @default.
• W3092121036 cites W1966373271 @default.
• W3092121036 cites W1967215446 @default.
• W3092121036 cites W1974645222 @default.
• W3092121036 cites W1975954480 @default.
• W3092121036 cites W1976610122 @default.
• W3092121036 cites W1988851913 @default.
• W3092121036 cites W1994028648 @default.
• W3092121036 cites W1994728769 @default.
• W3092121036 cites W1996854873 @default.
• W3092121036 cites W2001616049 @default.
• W3092121036 cites W2003325567 @default.
• W3092121036 cites W2026560684 @default.
• W3092121036 cites W2027816228 @default.
• W3092121036 cites W2036912028 @default.
• W3092121036 cites W2037992315 @default.
• W3092121036 cites W2038657121 @default.
• W3092121036 cites W2041752342 @default.
• W3092121036 cites W2055555969 @default.
• W3092121036 cites W2057075847 @default.
• W3092121036 cites W2059255008 @default.
• W3092121036 cites W2061053728 @default.
• W3092121036 cites W2066996091 @default.
• W3092121036 cites W2069956469 @default.
• W3092121036 cites W2070141491 @default.
• W3092121036 cites W2077034094 @default.
• W3092121036 cites W2078522610 @default.
• W3092121036 cites W2083089187 @default.
• W3092121036 cites W2086575224 @default.
• W3092121036 cites W2090885570 @default.
• W3092121036 cites W2094342305 @default.
• W3092121036 cites W2112724463 @default.
• W3092121036 cites W2127433483 @default.
• W3092121036 cites W2131794287 @default.
• W3092121036 cites W2166756343 @default.
• W3092121036 cites W2287377435 @default.
• W3092121036 cites W2331527365 @default.
• W3092121036 cites W2512902196 @default.
• W3092121036 cites W2560769164 @default.
• W3092121036 cites W2755138904 @default.
• W3092121036 cites W2765790093 @default.
• W3092121036 cites W2768866802 @default.
• W3092121036 cites W2807408763 @default.
• W3092121036 cites W2903785763 @default.
• W3092121036 cites W2996492475 @default.
• W3092121036 cites W4213255687 @default.
• W3092121036 cites W4232005894 @default.
• W3092121036 doi "https://doi.org/10.1016/j.biopha.2020.110790" @default.
• W3092121036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33035834" @default.
• W3092121036 hasPublicationYear "2020" @default.
• W3092121036 type Work @default.
• W3092121036 sameAs 3092121036 @default.
• W3092121036 citedByCount "6" @default.
• W3092121036 countsByYear W30921210362022 @default.
• W3092121036 crossrefType "journal-article" @default.
• W3092121036 hasAuthorship W3092121036A5022681943 @default.
• W3092121036 hasAuthorship W3092121036A5035229031 @default.
• W3092121036 hasAuthorship W3092121036A5054579471 @default.
• W3092121036 hasAuthorship W3092121036A5084361475 @default.
• W3092121036 hasBestOaLocation W30921210361 @default.
• W3092121036 hasConcept C109316439 @default.
• W3092121036 hasConcept C142724271 @default.
• W3092121036 hasConcept C1491633281 @default.
• W3092121036 hasConcept C152978389 @default.
• W3092121036 hasConcept C153911025 @default.
• W3092121036 hasConcept C16685009 @default.
• W3092121036 hasConcept C178790620 @default.
• W3092121036 hasConcept C181199279 @default.
• W3092121036 hasConcept C185592680 @default.
• W3092121036 hasConcept C202751555 @default.
• W3092121036 hasConcept C2583947 @default.
• W3092121036 hasConcept C2777318727 @default.
• W3092121036 hasConcept C2780070996 @default.
• W3092121036 hasConcept C2780484033 @default.
• W3092121036 hasConcept C2781065829 @default.
• W3092121036 hasConcept C29537977 @default.
• W3092121036 hasConcept C29730261 @default.
• W3092121036 hasConcept C53227056 @default.
• W3092121036 hasConcept C55493867 @default.
• W3092121036 hasConcept C71924100 @default.
• W3092121036 hasConcept C74864618 @default.
• W3092121036 hasConcept C86803240 @default.
• W3092121036 hasConceptScore W3092121036C109316439 @default.
• W3092121036 hasConceptScore W3092121036C142724271 @default.
• W3092121036 hasConceptScore W3092121036C1491633281 @default.
• W3092121036 hasConceptScore W3092121036C152978389 @default.
• W3092121036 hasConceptScore W3092121036C153911025 @default.

• next