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- W3092181552 abstract "Drug reaction with eosinophilia and systemic symptoms syndrome (DRESS) is a delayed infrequent potentially life-threatening idiosyncratic drug reaction. Aromatic anticonvulsants and allopurinol are the most frequent causative agents. However, various reports of antibiotic-induced DRESS are available. In this review, we try to summarize reports of antibacterial antibiotic-induced DRESS focusing on characteristics of DRESS induced by each antibiotic group.The data were collected by searching PubMed/MEDLINE and ScienceDirect. The keywords used as search terms were DRESS syndrome, drug-induced hypersensitivity syndrome (DIHS), antibiotics, antimicrobial, and names of various antimicrobial groups. Finally, 254 relevant cases with a definite or probable diagnosis of DRESS based on RegiSCAR criteria were found until 30 May 2020 and reviewed.Totally, 254 cases of antibacterial antibiotic-induced DRESS are reported. Most of them are related to antituberculosis drugs, vancomycin, and sulfonamides, respectively. Rash and fever were most frequent clinical findings. Eosinophilia and liver injury were the most reported hematologic and visceral organ involvement, respectively. Most of the patients are managed with systemic corticosteroids. The death occurred in 16 patients which most of them experienced liver or lung involvement. The reactivation of various viruses especially HHV-6 is reported in 33 cases. The mean latency period was 29 days. It is necessary to perform thorough epidemiological, genetic, and immunological studies, also systematic case review and causality assessment, as well as well-designed clinical trials for better management of antibiotic-induced DRESS." @default.
- W3092181552 created "2020-10-15" @default.
- W3092181552 creator A5045277003 @default.
- W3092181552 creator A5053758895 @default.
- W3092181552 creator A5062602431 @default.
- W3092181552 creator A5080572893 @default.
- W3092181552 date "2020-10-06" @default.
- W3092181552 modified "2023-10-14" @default.
- W3092181552 title "Antibacterial antibiotic-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a literature review" @default.
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