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• W3092216478 abstract "Abstract The application of natural preservatives has become an attractive method for controlling postharvest decay of fruits and vegetables. Allicin, the main active ingredient of allium plants, has broad‐spectrum antifungal activity. However, the unstable properties of allicin limit its wide application. In this study, 1‐[(R)‐ethylsulfinyl]sulfanylethane, a structurally stable derivative of allicin, was used to explore its antifungal activity and potential mechanism on the expansion of Penicillium expansum . We demonstrated the antifungal activity of 1‐[(R)‐ethylsulfinyl]sulfanylethane through in vitro antifungal experiments. At the concentration is 2 mg/L, 1‐[((R)‐ethylsulfinyl]sulfanyl]ethane can completely inhibit spore germination and mycelial growth, whereas the concentration of allicin needs to reach 16 mg/L. Fungal Biochemical assay indicated that decrease of mitochondrial membrane potential, overgeneration of reactive oxygen species, decrease of adenosine triphosphate and glutathione content, increase of superoxide dismutase, catalase, and malondialdehyde content. The results revealed that 1‐[(R)‐ethylsulfinyl]sulfanylethane induced mitochondrial dysfunction and oxidative stress in P. expansum . Due to its excellent antifungal activity, 1‐[((R)‐ethylsulfinyl]sulfanyl]ethane might be developed as a substitute for fungicides against P. expansum in postharvest fruit storage." @default.
• W3092216478 created "2020-10-15" @default.
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• W3092216478 date "2020-10-06" @default.
• W3092216478 modified "2023-09-26" @default.
• W3092216478 title "Antifungal activity of an allicin derivative against Penicillium expansum via induction of oxidative stress" @default.
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• W3092216478 doi "https://doi.org/10.1002/jobm.202000267" @default.
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