FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3092227531> ?p ?o ?g. }

• W3092227531 endingPage "120450" @default.
• W3092227531 startingPage "120450" @default.
• W3092227531 abstract "Mesenchymal stem cells are the focus of intense research in bone development and regeneration. The potential of microparticles as modulating moieties of osteogenic response by utilizing their architectural features is demonstrated herein. Topographically textured microparticles of varying microscale features are produced by exploiting phase-separation of a readily soluble sacrificial component from polylactic acid. The influence of varying topographical features on primary human mesenchymal stem cell attachment, proliferation and markers of osteogenesis is investigated. In the absence of osteoinductive supplements, cells cultured on textured microparticles exhibit notably increased expression of osteogenic markers relative to conventional smooth microparticles. They also exhibit varying morphological, attachment and proliferation responses. Significantly altered gene expression and metabolic profiles are observed, with varying histological characteristics in vivo. This study highlights how tailoring topographical design offers cell-instructive 3D microenvironments which allow manipulation of stem cell fate by eliciting the desired downstream response without use of exogenous osteoinductive factors." @default.
• W3092227531 created "2020-10-15" @default.
• W3092227531 creator A5002789813 @default.
• W3092227531 creator A5002974001 @default.
• W3092227531 creator A5004331670 @default.
• W3092227531 creator A5008665215 @default.
• W3092227531 creator A5015478848 @default.
• W3092227531 creator A5016333701 @default.
• W3092227531 creator A5019725924 @default.
• W3092227531 creator A5023518920 @default.
• W3092227531 creator A5031979025 @default.
• W3092227531 creator A5034434967 @default.
• W3092227531 creator A5040939196 @default.
• W3092227531 creator A5052543743 @default.
• W3092227531 creator A5059665300 @default.
• W3092227531 creator A5062143994 @default.
• W3092227531 creator A5075605485 @default.
• W3092227531 creator A5079400676 @default.
• W3092227531 creator A5085660248 @default.
• W3092227531 creator A5091151866 @default.
• W3092227531 date "2021-01-01" @default.
• W3092227531 modified "2023-10-17" @default.
• W3092227531 title "Designing topographically textured microparticles for induction and modulation of osteogenesis in mesenchymal stem cell engineering" @default.
• W3092227531 cites W1611854178 @default.
• W3092227531 cites W1842881974 @default.
• W3092227531 cites W1976709402 @default.
• W3092227531 cites W1989485116 @default.
• W3092227531 cites W1992747064 @default.
• W3092227531 cites W1998559371 @default.
• W3092227531 cites W2003240064 @default.
• W3092227531 cites W2007876874 @default.
• W3092227531 cites W2013309732 @default.
• W3092227531 cites W2015979204 @default.
• W3092227531 cites W2019315690 @default.
• W3092227531 cites W2019553776 @default.
• W3092227531 cites W2034091561 @default.
• W3092227531 cites W2042203980 @default.
• W3092227531 cites W2043562635 @default.
• W3092227531 cites W2046377580 @default.
• W3092227531 cites W2047961352 @default.
• W3092227531 cites W2060341044 @default.
• W3092227531 cites W2061922416 @default.
• W3092227531 cites W2063221437 @default.
• W3092227531 cites W2079273064 @default.
• W3092227531 cites W2082706597 @default.
• W3092227531 cites W2088840362 @default.
• W3092227531 cites W2100454719 @default.
• W3092227531 cites W2106100463 @default.
• W3092227531 cites W2106266445 @default.
• W3092227531 cites W2118966122 @default.
• W3092227531 cites W2125899377 @default.
• W3092227531 cites W2129648738 @default.
• W3092227531 cites W2134208433 @default.
• W3092227531 cites W2138110959 @default.
• W3092227531 cites W2157043934 @default.
• W3092227531 cites W2159034171 @default.
• W3092227531 cites W2162143298 @default.
• W3092227531 cites W2168590651 @default.
• W3092227531 cites W2171093380 @default.
• W3092227531 cites W2276063522 @default.
• W3092227531 cites W2289421529 @default.
• W3092227531 cites W2327951769 @default.
• W3092227531 cites W2336645021 @default.
• W3092227531 cites W2401482619 @default.
• W3092227531 cites W2408382340 @default.
• W3092227531 cites W2517690144 @default.
• W3092227531 cites W2520035938 @default.
• W3092227531 cites W2521242642 @default.
• W3092227531 cites W2587156779 @default.
• W3092227531 cites W2588168453 @default.
• W3092227531 cites W2588575372 @default.
• W3092227531 cites W2761557397 @default.
• W3092227531 cites W2767428727 @default.
• W3092227531 cites W2772931378 @default.
• W3092227531 cites W2775703408 @default.
• W3092227531 cites W2792508496 @default.
• W3092227531 cites W2794019594 @default.
• W3092227531 cites W2804606320 @default.
• W3092227531 cites W2805418159 @default.
• W3092227531 cites W2806664373 @default.
• W3092227531 cites W2813985977 @default.
• W3092227531 cites W2898666867 @default.
• W3092227531 cites W2901642736 @default.
• W3092227531 cites W2903883818 @default.
• W3092227531 cites W2913379012 @default.
• W3092227531 cites W2923270692 @default.
• W3092227531 cites W2944568864 @default.
• W3092227531 cites W2947081105 @default.
• W3092227531 cites W2949840382 @default.
• W3092227531 cites W2955531480 @default.
• W3092227531 cites W2972782401 @default.
• W3092227531 cites W2974361058 @default.
• W3092227531 cites W2991416247 @default.
• W3092227531 cites W3025950793 @default.
• W3092227531 cites W3037843001 @default.
• W3092227531 cites W3037871209 @default.
• W3092227531 cites W3102159917 @default.
• W3092227531 cites W584794406 @default.

• next