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- W3092281208 abstract "Atopy can manifest as allergic asthma or allergic rhinitis (AR), and both disorders frequently co-occur. AR in childhood is known to strongly predispose individuals to developing asthma in adulthood. The allergic airway syndrome has both inherited and environmental contributions. A clearer understanding of the risk factors that underpin atopic airway disease and how the parts of the airway interact is a necessary step towards a more rational approach to treatment. Researchers have hypothesised a number of different ways in which the upper and lower airways may influence each other in AR and asthma. That nasal pathophysiology has effects on the lower airways in asthmatics has been repeatedly shown to be true. For individuals in whom asthma and rhinitis co-occur, the disorder is typically of greater severity and it costs more to treat. The unified airway model is significant in considering how best to treat, prevent and manage asthma and rhinitis. Since it is common for allergic rhinitis to occur in association with asthma or to occur before asthma develops, the Allergic Rhinitis and Its Impact on Asthma (ARIA) organisation, with the backing of the WHO, advocates seeing AR as predicting the risk of asthma and examining for bronchial disease in any patient who presents with AR." @default.
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- W3092281208 date "2020-10-09" @default.
- W3092281208 modified "2023-10-03" @default.
- W3092281208 title "Upper and Lower Airways Interaction: Is the United Airway Disease Concept a Reflection of Reality? How Important Is It?" @default.
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- W3092281208 doi "https://doi.org/10.1007/978-3-030-50899-9_40" @default.
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